Results 21 to 30 of about 105,125 (248)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Familia,

Cuadernos de Teología - Universidad Católica del Norte, 2009
La familia, a lo largo de la historia ha variado en sus funciones, roles, en sus relaciones tanto internas como externas y en sus articulaciones con otras instituciones. El definirla resulta difícil dado los cambios evidenciados, resulta más sencillo caracterizarla genéricamente como unidad básica de la organización social y como agente formadora de ...
openaire   +3 more sources

Ensayo clínico aleatorio para evaluar la eficacia de una intervención educativa desarrollada en atención primaria sobre asmáticos adultos

Atención Primaria, 2014
Objetivo: Evaluar el efecto de una intervención educativa específica sobre el control del asma y la calidad de vida. Diseño: Ensayo clínico con asignación aleatoria de pacientes asmáticos, a un grupo de intervención educativa (GI) y otro de control (GC).
Gloria Cano Fuentes, Carmen Dastis Bendala, Isabel Morales Barroso, M. Luisa Manzanares Torné, Andrés Fernández Gregorio, Leticia Martín Romana   +5 more
doaj   +1 more source

Improving Oxygen Barrier Performance of Polylactide Film by Using Bleached and Unbleached Nanocellulose From Grape Pomace

Journal of Applied Polymer Science, EarlyView.
Bleached and unbleached nanocelluloses were produced from the exhausted grape pomace and applied as coatings on PLA substrates for sustainable food packaging. Unbleached nanocelluloses were more hydrophobic and amorphous than bleached ones. The resulting bio‐based bleached nanocellulose‐coated PLA films showed a 68% reduction in O2 permeability ...
Jingwen Chen, Nadia O. Okamoto‐Schalch, Maria Gabriela B. Dalben, Sandra Domenek, Chloé Chevigny, Giana Almeida, Milena Martelli‐Tosi   +6 more
wiley   +1 more source

Evaluación de la competencia digital en futuros docentes: un análisis exploratorio en educación superior.

Edutec
En el contexto educativo actual, la competencia digital es esencial en la formación de futuros docentes. Este estudio explora las percepciones de 179 estudiantes (121 mujeres y 58 hombres) de los grados en Educación Primaria y Educación Infantil del ...
José Hidalgo Navarrete, Jesús Juan Risueño Martínez, Elena Moreno Fuentes   +2 more
doaj   +1 more source

Organización de la Atención Primaria en tiempos de pandemia

Atención Primaria, 2021
Resumen: La pandemia por COVID-19 ha forzado la adopción de cambios drásticos en Atención Primaria, modificando la organización y las dinámicas de trabajo establecidas hasta entonces.
Txema Coll Benejam, Jesús Palacio Lapuente, Rosa Añel Rodríguez, Montse Gens Barbera, Juan José Jurado Balbuena, Aina Perelló Bratescu   +5 more
doaj   +1 more source

AI Hallucinations in Tourism: How Errors Impact Consumer Trust and Recommendation Acceptance

Journal of Consumer Behaviour, EarlyView.
ABSTRACT Generative artificial intelligence (GenAI) is quickly transforming travel planning; however, its outputs can include hallucinations, which are plausible yet false statements that can undermine user judgement. Eliminating hallucinations in GenAI technology is currently impossible.
Francisco Rejón‐Guardia, Sebastian Molinillo, Rafael Anaya‐Sánchez   +2 more
wiley   +1 more source

Do Policy Capacities Matter for Federal Policy Design? Evidence From the Implementation of Three Social Policies in Brazil

Public Administration and Development, EarlyView.
ABSTRACT Bringing together the literature on policy design, policy capacity and policy making in multilevel systems, this paper argues that the effectiveness of policy design in federal countries depends, ceteris paribus, on the adequacy of federal and local policy capacities.
Giliberto Capano, Vanessa Elias de Oliveira   +1 more
wiley   +1 more source

Policy Capacity Matters Differently Over Time: The Emergence and Persistence of Participatory Budgeting in China

Public Administration and Development, EarlyView.
ABSTRACT The persistence of participatory budgeting (PB) in selected Chinese localities challenges the conventional wisdom that deliberative democratic practices can only take root in liberal political environments. Yet, existing literature has not sufficiently elucidated the factors underpinning the rise and sustained operation of PB in this seemingly
Yifei Yan, Alfred M. Wu, Biao Huang, Fangxin Yi   +3 more
wiley   +1 more source

Digitising biological collections to advance National Species Inventories: A case study from the flora of Chile

PLANTS, PEOPLE, PLANET, EarlyView.
In response to Chile's public policy to establish a national biodiversity inventory and monitoring system, we launched the HerbarioDigital.cl portal. We have digitised over 120,000 specimens representing more than 3,900 species from two Chilean herbaria, integrating them through a curated local taxonomic index.
Ricardo A. Segovia, Juan M. Sáez, Francisco A. Squeo, Alicia E. Marticorena, Julián Caro, Pablo C. Guerrero   +5 more
wiley   +1 more source