Results 91 to 100 of about 604,020 (263)

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

Distinct clinical characteristics of familial and solitary patients with bipolar disorder

Psychiatry and Behavioral Sciences, 2011
Objective: Major mental disorders including bipolar disorder aggregate in families. There are also non-familial, solitary cases and familial and non-familial cases may differ. Most of the studies regarding familiality in bipolar disorder targeted similar
Murat İlhan Atagun, Esra Sena Cevahirli, Tuğba Kara, Sencer Tabakcı, Ozlem Devrim Balaban, Dilek Yeşilbaş   +5 more
doaj   +1 more source

Representation of Sickle Cell Disease Patients in Pediatric and Adult Care: What We Discovered Using Informatics for Integrating Biology and the Bedside (i2b2) Data

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Transitioning from pediatric to adult care is a high‐risk period for individuals with sickle cell disease (SCD). An initial observation at one academic medical center suggested a sex‐based disparity in clinic populations, prompting a national investigation.
Laurie J. Duckworth, Kholod Alhassan, Ada De La Osa, John Stephen, Yue Yao, Diana J. Wilkie   +5 more
wiley   +1 more source

LDLR-Gene therapy for familial hypercholesterolaemia: Problems, progress, and perspectives [PDF]

, 2010
Coronary artery diseases (CAD) inflict a heavy economical and social burden on most populations and contribute significantly to their morbidity and mortality rates.
Charles Coutelle, Harbottle, R, Anna L David, Themis, M, Al-Allaf, FA, Waddington, SN, David, A, Faisal A Al-Allaf, Michael Themis, Coutelle, C, Simon N Waddington, Richard Harbottle   +11 more
core   +1 more source

A model of care for familial hypercholesterolaemia: key role for clinical biochemistry

, 2012
Familial hypercholesterolaemia (FH) is a dominantly inherited disorder present from birth that causes marked elevation in plasma low-density lipoprotein (LDL) cholesterol concentrations and premature coronary heart disease.
Clifton, P., O'Brien, R., Hamilton-Craig, I., Watts, G., Sullivan, D., van Bockxmeer, F., Burnett, J., Poplawski, N., George, P.   +8 more
core  

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome) [PDF]

, 2010
Causative genetic variants have to date been identified for only a small proportion of familial colorectal cancer (CRC). While conditions such as Familial Adenomatous Polyposis and Lynch syndrome have well defined genetic causes, the search for variants ...
Darin Taverna, Hopper, John L., Young, Bruce W., Taverna, Darin, Pelzer, E., Walters, Rhiannon, Pavluk, E, Roberts, A., Parry, Susan, Daniel D. Buchanan, Lindblom, Annika, Derek Nancarrow, Lindblom, A, Annika Lindblom, Diane McKeone, Gattas, M, Woodall, Sonja, Drini, Musa, Nancarrow, D., Duggan, David, Erika Pavluk, Gattas, M., Walsh, Michael D., Muir, Amanda, Joanne P. Young, John D. Potter, Jenkins, Mark A., Buchanan, DD, Roberts, Aedan, Pelzer, E, Hopper, JL, Rosty, C., Finlay Macrae, Arnold, J, Clendenning, Mark, Duggan, D, John L. Hopper, Jenkins, Mark, Jeremy R. Jass, Muir, A, Taverna, D., Bruce W. Young, Kerry Phillips, George, Jill, Potter, John D., Phillips, K., Aedan Roberts, Suthers, GK, McKeone, Diane, Tucker, Kathy, Macrae, Finlay, Parry, S, Phillips, K, Amanda Muir, Buchanan, D., Rosty, C, Elise Pelzer, Young, B., Jack Goldblatt, Gattas, Michael, Sonja Woodall, Suthers, G., Newcomb, P, Pavluk, Erika, Clendenning, M, David Duggan, Walters, R, Tucker, K, Newcomb, Polly, Buchanan, Daniel, Hopper, J., Young, JP, Jenkins, M., Duggan, D., Goldblatt, Jack, Young, Bruce, Jenkins, MA, Phillips, Kerry, Michael Gattas, Musa Drini, Mark Clendenning, et al., Rhiannon Walters, Roberts, A, Goldblatt, J, Jass, JR, Buchanan, Daniel D., Suthers, Graeme K., Walsh, M., Graeme K. Suthers, Goldblatt, J., Buchanan, Daniel D, McKeone, D., Kathy Tucker, Potter, JD, Jenkins, Mark A, McKeone, D, Nancarrow, Derek, Young, BW, Walsh, Michael, Susan Parry, Walsh, MD, Drini, M, Mark A. Jenkins, Clendenning, M., Jass, Jeremy R., Pelzer, Elise, MacRae, F, Michael D. Walsh, Jill George, Taverna, D, Nancarrow, D, George, J, Polly Newcomb, Jass, J., Arnold, Julie, Woodall, S, Rosty, Christophe, George, J., Christophe Rosty, other, and, Julie Arnold, Walters, R.   +122 more
core   +2 more sources

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Frequency of Familial Gastric Cancer

, 2013
About 80–90 % of gastric cancer appears as sporadic form, and 10–20 % with a familial setting; however, considering the different worldwide countries, this frequency appears extremely variable.
Marrelli D, Corso G, Daniele Marrelli, Giovanni Corso   +3 more
core   +1 more source

A Novel PKD1 Mutation Associated With Autosomal Dominant Kidney Disease and Cerebral Cavernous Malformation

Frontiers in Neurology, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the presence of renal cysts and specific extrarenal abnormalities.
Christian Thomas, Andrea Zühlsdorf, Konstanze Hörtnagel, Lejla Mulahasanovic, Oliver M. Grauer, Philipp Kümpers, Heinz Wiendl, Sven G. Meuth   +7 more
doaj   +1 more source