Results 221 to 230 of about 604,020 (263)

In vitro analysis of the effects of intronic variants c.940+3_940+6del, c.941-3C>G, and c.2389+5G>A in the LDLR gene on pre-mRNA splicing using a minigene assay. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Danilchenko VY, Ivanoshchuk DE, Timoshchenko OV, Panina EA, Orlov PS, Shakhtshneider EV.   +5 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Correction to "Discovering Hereditary Risk Through Surveillance: A Prospective Genetic Analysis of Individuals With Familial Pancreatic Cancer". [PDF]

United European Gastroenterol J
europepmc   +1 more source

Familial melanoma: genetic, clinical, and dermoscopic insights and follow-up. [PDF]

Front Med (Lausanne)
Raika AE, de Las Heras Alonso ME, Sproge D, Bataraga E.   +3 more
europepmc   +1 more source

Familial acromegaly with a novel <i>PRKAR1A</i> splice-acceptor variant and marked intrafamilial phenotypic variability. [PDF]

JCEM Case Rep
Jha V, Barry S, Chatterjee D, Kaur V, Korbonits M, Dutta P.   +5 more
europepmc   +1 more source

Two Cases of Multiple Sclerosis in a Family With X-Linked Charcot-Marie-Tooth Disease. [PDF]

Neurol Genet
Menih M, Hojs Fabjan T, Maver A, Peterlin B.   +3 more
europepmc   +1 more source