Results 251 to 260 of about 1,069,656 (317)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Prime editing of the common Familial Dysautonomia-causing c.2204 + 6T > C splicing mutation. [PDF]

Orphanet J Rare Dis
Peretto L, Pinotti M, Balestra D.
europepmc   +1 more source

Clinical Impact of Familial Hypercholesterolemia on Lower Extremity Artery Disease in Premature Patients. [PDF]

Ann Vasc Dis
Ito E, Ohki T, Yoshida H, Kaneko K.
europepmc   +1 more source

Myocardial Ischemia in Young Women With Familial Hypercholesterolemia: Similar Presentation and Divergent Treatment Response. [PDF]

JACC Case Rep
Flores-Renteria LY, Villegas-Chavez CA, Mendoza-Salgado JU, Gamboa-Hernandez OJ, Lara-Ameca VJ, Quiroz-Martinez VA, Zamora KDV.   +6 more
europepmc   +1 more source

Exploring the relationship between family support and eating behaviors among college students with subjective well-being as the central mediating variable. [PDF]

Front Psychol
Xue C, Peng H, Li G, Fang J, Wang X, Zhao B, Liu P, Liang Z, Tang W.   +8 more
europepmc   +1 more source

The effect of statins on the risk of bleeding in cerebral cavernous malformations: A systematic review and meta-analysis. [PDF]

Surg Neurol Int
Erel BC, Uslu I, Kara B, Turkmenel MG, Celikkiran ZE, Gultekin E, Gayi S, Kilic DB, Kilic B, Yangi DDD, Yangi K.   +10 more
europepmc   +1 more source

Positive Predictive Values of Familial Hypercholesterolemia Diagnoses in the Danish National Patient Registry and the Danish Familial Hypercholesterolemia Registry - A Validation Study. [PDF]

Clin Epidemiol
Knold J, Bork C, Snoer M, Heitmann M, Bang LE, Kanstrup H, Hansen KL, Hedegaard BS, Thomsen KK, Lauridsen BK, Bovin A, Lundquist AA, Al Tamimi HKS, Brorholt-Petersen JU, Christensen TE, Bertelsen MLN, Gohr T, Ellermann A, Hansen CP, Weis A, Nielsen PR, Schmidt EB, Bundgaard H, Henriksen FL, Danish Familial Hypercholesterolemia Study Group.   +24 more
europepmc   +1 more source