Results 281 to 290 of about 52,688 (314)

Cholesterol lowering in familial hypercholesterolemia: studies in man and rabbit

, 1990
M.J.T.M. Mol
openalex   +1 more source

Course of Pregnancy in a Woman With Familial Chylomicronemia Syndrome Treated With Plozasiran, a Small Interfering RNA Against ApoC3

JIMD Reports, Volume 67, Issue 1, January 2026.
ABSTRACT Persistent chylomicronemia is associated with severe hypertriglyceridemia (sHTG) and plasma triglycerides (TG) levels sustainably > 10 mmol/L (880 mg/dL) despite lipid lowering therapies. The main risk of persistent chylomicronemia is acute pancreatitis (AP). During the second and third trimester of pregnancy, TG levels significantly increase,
Miriam Larouche, Diane Brisson, Nathalie Roy, Claudy Grenon, Paul Poirier, Ma'an Muhsin, Daniel Gaudet   +6 more
wiley   +1 more source

Treating Familial Hypercholesterolemia: An Insistence on Persistence. [PDF]

JACC Case Rep
Spitz JA.
europepmc   +1 more source

Engaging Patients in Learning Health Systems Research Using Human Centered Design: A Scoping Review

Learning Health Systems, Volume 10, Issue 1, January 2026.
ABSTRACT Introduction The “Learning Health System” (LHS) relies on meaningful patient and public engagement to foster innovation in healthcare. However, effective methods for involving these stakeholders in LHS research are unclear. This scoping review examines the use of Human‐Centered Design (HCD) to engage patients and the public in LHS research ...
Dorsa Moslehi, Lynn A. Volk, Samantha A. Lee, Paul A. Bain, Jeanne‐Marie Guise   +4 more
wiley   +1 more source

Carotid Plaque, Coronary Calcium, and Coronary Plaque: Triple Threat of Atherosclerosis in Familial Hypercholesterolemia. [PDF]

JACC Asia
Mszar R, Rana JS.
europepmc   +1 more source

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

Medicinal Research Reviews, Volume 46, Issue 1, Page 238-271, January 2026.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg, Tracie Widjaja, Adriaan P. IJzerman, Daan van der Es   +3 more
wiley   +1 more source

Two Cases of Heterozygous Familial Hypercholesterolemia in Children Effectively Managed With Pitavastatin and Ezetimibe Combination Therapy. [PDF]

Clin Case Rep
Nishioka K, Kondo S, Irie K, Kondo T, Iwase T, Tani R, Inoue T, Matsunaga K, Minamino T, Kusaka T.   +9 more
europepmc   +1 more source

Unfermented High‐Fiber Rye Crispbread Increases Plasma HDL and Reduces Hepatic Lipids Compared to Refined Wheat in Rats Fed a High‐Fat Diet

Molecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
This study compared the effects of whole grain fermented and unfermented rye crispbread with refined wheat on body weight and lipid metabolism in rats. Unfermented rye crispbread increased plasma HDL‐cholesterol and reduced hepatic triacylglycerols and cholesterol compared to refined wheat, indicating favorable lipid‐modulating effects.
Fidèle Almasri, Eleonora Aimaretti, Nadine Sus, Erik Schéle, Suzanne L. Dickson, Rikard Landberg, Massimo Collino, Jan Frank   +7 more
wiley   +1 more source

Assessments of Atherosclerosis and Treatment Strategies for Heterozygous Familial Hypercholesterolemia. [PDF]

J Atheroscler Thromb
Tada H, Harada-Shiba M.
europepmc   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, Volume 10, Issue 2, 22 January 2026.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source