Results 71 to 80 of about 2,043 (190)
Journal of Cellular Physiology, Volume 239, Issue 8, August 2024.Abstract The mechanistic relationships between the progression of growth chondrocyte differentiation, matrix mineralization, oxidative metabolism, and mitochondria content and structure were examined in the ATDC5 murine chondroprogenitor cell line. The progression of chondrocyte differentiation was associated with a statistically significant (p ≤ 0.05)
Kevin Blank +5 more
wiley +1 more source
Heritable and acquired disorders of phosphate metabolism: Etiologies involving FGF23 and current therapeutics [PDF]
, 2017 Phosphate is critical for many cellular processes and structural functions, including as a key molecule for nucleic acid synthesis and energy metabolism, as well as hydroxyapatite formation in bone.
Clickenbeard, Erica L. +1 more
core +2 more sources
The impact of metabolic disorders on management of periodontal health in children
Pediatric Discovery, Volume 2, Issue 1, March 2024.Metabolic diseases in children and adolescents may increase the risk of periodontal disease by affecting immunity and oral microbial colonization. Abstract Periodontitis is a chronic inflammatory disease caused by plaque biofilm which shares risk factors with systemic chronic diseases such as diabetes, cardiovascular disease, and osteoporosis.
Yunyan Zhang +2 more
wiley +1 more source
Phosphate diabetes: a clinical case of family hypophosphatemic rickets
Perm Medical Journal, 2023 Objective. To describe the clinical picture of the course of hypophosphatemic rickets in two members of the same family. Phosphate diabetes is a rare hereditary pathology of mineral and bone metabolism. Materials and methods. There is presented a clinical picture of the course of hypophosphatemic rickets in two members of the same family. ...
openaire +1 more source
Pediatric Investigation, Volume 8, Issue 1, Page 66-71, March 2024.Children with critical rare diseases often have multiple organ dysfunction and high mortality. At present, there are some problems in the diagnosis and treatment of critical rare diseases of children in China, such as long diagnosis time, high misdiagnosis rate, limited treatment methods, and heavy disease burden.
Yingchao Liu, Suyun Qian
wiley +1 more source
Hereditary hypophosphatemia in Norway: A retrospective population-based study of genotypes, phenotypes, and treatment complications [PDF]
, 2015 Objective: Hereditary hypophosphatemias (HH) are rare monogenic conditions characterized by decreased renal tubular phosphate reabsorption. The aim of this study was to explore the prevalence, genotypes, phenotypic spectrum, treatment response, and ...
Bjerknes, Robert +3 more
core +1 more source
FGF23 and its role in X-linked hypophosphatemia-related morbidity [PDF]
, 2019 Background: X-linked hypophosphatemia (XLH) is an inherited disease of phosphate metabolism in which inactivating mutations of the Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) gene lead to local and systemic effects including impaired ...
Ariceta Iraola, Gema +10 more
core +3 more sources
The management of siblings with familial hypophosphatemic rickets.
Helvetica paediatrica acta, 1983 Two siblings (boy and girl) born to a mother with familial hypophosphatemic rickets had abnormal values of serum phosphorus and serum alkaline phosphatase at the age of six weeks. At this age therapy with 1 alpha-hydroxycholecalciferol (1 alpha OHD3) and phosphate was started resulting in both siblings having normal growth of body length and ...
Lapatsanis, P. D. +3 more
openaire +2 more sources
Genetic causes of hypophosphatemia [PDF]
Phosphate is a key component of mineralized tissues and is also part of many organic compounds. Phosphorus homeostasis depends especially upon intestinal absorption, and renal excretion, which are regulated by various hormones, such as PTH, 1,25 ...
Puente Ruiz, Nuria +2 more
core +1 more source
Three-Year Successful Cinacalcet Treatment of Secondary Hyperparathyroidism in a Patient with X-Linked Dominant Hypophosphatemic Rickets: A Case Report [PDF]
, 2014 Hypophosphatemic rickets (HR) is a rare inherited disorder characterized by a classic rickets phenotype with low plasma phosphate levels and resistance to treatment with vitamin D.
Grove-Laugesen, Diana, Rejnmark, Lars
core +2 more sources