Results 1 to 10 of about 21,064 (109)

Potts Shunt in Children With Familial Primary Pulmonary Hypertension: A Case Report and Brief Literature Review

Journal of Pediatrics Review, 2021
Introduction: The primary concern about Familial Pulmonary Arterial Hypertension (FPAH) is the development of right heart failure, which ultimately leads to sudden death.
Yazdan Ghandi, Ali Arjmand Shabestari, Mahya Mobinikhaledi   +2 more
doaj   +1 more source

Pulmonary Arterial Hypertension: A Review Article [PDF]

Reviews in Clinical Medicine, 2018
Pulmonary arterial hypertension (PAH) is characterized by the mean pulmonary artery pressure of more than 25 mmHg and pulmonary artery wedge pressure of less than 15 mmHg evidenced by right-heart catheterization.
Samaneh Sajjadi, Sepideh Hejazi, Ghazaleh Azami, Mina Akbari, Fatemeh Akbari   +4 more
doaj   +1 more source

Pulmonary Capillary Hemangiomatosis as a Rare Underlying Cause of Primary Pulmonary Hypertension: A Case Report in an Adolescent [PDF]

Iranian Journal of Medical Sciences
Despite its rarity, pulmonary capillary hemangiomatosis (PCH) presents a significant diagnostic challenge. Due to its similarity to other pulmonary vascular diseases, such as pulmonary veno-occlusive disease, it is characterized by abnormal pulmonary ...
Mohammad Mahdavi, Hossein Shahzadi, Mohsen Ghasemnezhad, Soheila Hoseinzadeh Moghadam   +3 more
doaj   +1 more source

Hemodynamic trajectories and outcomes in patients with pulmonary arterial hypertension

Pulmonary Circulation, 2020
The relative pulmonary to systemic pressure ratio (mean pulmonary arterial pressure/mean arterial pressure) has been proven to be valuable in cardiac surgery.
Myriam Amsallem, Shadi P. Bagherzadeh, David Boulate, Andrew J. Sweatt, Kristina T. Kudelko, Yon K. Sung, Jeffrey A. Feinstein, Elie Fadel, Olaf Mercier, Andre Denault, Francois Haddad, Roham Zamanian   +11 more
doaj   +1 more source

Severe pulmonary hypertension after the discovery of the familial primary pulmonary hypertension gene [PDF]

European Respiratory Journal, 2001
The recent discoveries of the familial primary pulmonary hypertension gene and somatic mutations in key cell growth and cell death regulatory genes in primary pulmonary hypertension have added a new dimension to severe pulmonary hypertension research.
R M, Tuder, M E, Yeager, M, Geraci, H A, Golpon, N F, Voelkel   +4 more
openaire   +2 more sources

Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension

Respiratory Research, 2001
Several recent papers have shown that both familial primary pulmonary hypertension (FPPH) and sporadic primary pulmonary hypertension (PPH) may have a common etiology that is associated with the inheritance and/or spontaneous development of germline ...
Meyrick Barbara, Caestecker Mark De
doaj   +1 more source

Genomic approaches to research in pulmonary hypertension

Respiratory Research, 2001
Genomics, or the study of genes and their function, is a burgeoning field with many new technologies. In the present review, we explore the application of genomic approaches to the study of pulmonary hypertension (PH).
Tuder Rubin M, Yeager Michael E, Hoshikawa Yasushi, Gao Bifeng, Geraci Mark W, Voelkel Norbert F   +5 more
doaj   +1 more source

Primary pulmonary hypertension in families with hereditary haemorrhagic telangiectasia [PDF]

European Respiratory Journal, 2004
Primary pulmonary hypertension (PPH) is a rare but severe and progressive disease characterised by obstructive lesions of small pulmonary arteries. Patients with PPH often have mutations in the bone morphogenetic protein receptor type II (BMPR2) gene, whereas some carry mutations in the activin receptor-like kinase 1 (ALK‐1) gene, generally associated ...
S A, Abdalla, C J, Gallione, R J, Barst, E M, Horn, J A, Knowles, D A, Marchuk, M, Letarte, J H, Morse   +7 more
openaire   +2 more sources

Two Cases of Familial Primary Pulmonary Hypertension

Journal of UOEH, 2004
Case 1, a 28-year-old woman (third daughter of Case 2) delivered her first child in September 2000, but leg edema and dyspnea on exertion appeared the following January. At the time of our first examination of the patient in May 2001, a chest X-ray showed cardiomegaly and pulmonary artery enlargement.
Kazuhito, Yamashita, Hiromi, Tasaki, Takahiro, Kubara, Yasuhide, Nakashima   +3 more
openaire   +3 more sources

State of the Art in Pulmonary Arterial Hypertension: Molecular Basis, Imaging Modalities, and Right Heart Failure Treatment

Biomedicines
Pulmonary hypertension (PH) is broadly defined as a mean pulmonary arterial pressure (mPAP) exceeding 20 mm Hg at rest. Pulmonary arterial hypertension (PAH) is a specific subset of PH characterized by a normal pulmonary arterial wedge pressure (PAWP ...
Melika Shafeghat, Yasmin Raza, Roberta Catania, Amir Ali Rahsepar, Blair Tilkens, Michael J. Cuttica, Benjamin H. Freed, Jingbo Dai, You-Yang Zhao, James C. Carr   +9 more
doaj   +1 more source