Results 141 to 150 of about 4,443,508 (280)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Ausência de associação ou associação inversa entre o LDL-C e a mortalidade no idoso: a queda do mito?

Revista Portuguesa de Medicina Geral e Familiar, 2017
Micaela Prata, Mafalda Gonçalves
doaj   +1 more source

Niche Breadth and Olfactory Context Shape Informed Passive Dispersal. [PDF]

Ecol Lett
Zalewska K, Skoracka A, Bonte D, Puchalska E, Lewandowski M, Kuczyński L.   +5 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Subtle Gaze and Pupil Dynamics: Detecting Recognition of Familiar Faces with Moving Serial Visual Presentation. [PDF]

J Cogn
Chen IY, Mathôt S, Akyürek EG.
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Can you read my poker-face? Adapting the still-face paradigm to explore dog's interspecific communication. [PDF]

Anim Cogn
Canori C, Pedretti G, Travain T, Annoni C, Sabbadini L, Valsecchi P.   +5 more
europepmc   +1 more source

Entrevista a Jaime Breilh: primera parte [PDF]

, 2013
Revista Archivos de Medicina Familiar y General
core  

Avaliação familiar: índice de apgar familiar

, 2007
A necessidade de centrar os cuidados na comunidade pressupõe trabalho direccionado à família como grupo e não como a soma dos seus membros. Podendo a família ser receptora e prestadora de cuidados, torna-se fundamental uma avaliação eficiente. O enfermeiro de família deve ter sempre presente que as intervenções de enfermagem optimizam-se quando toda a ...
Fernandes, Adília, Magalhães, Carlos Pires, Antão, Celeste, Anes, Eugénia   +3 more
openaire   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source