Results 131 to 140 of about 270,260 (303)
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
This study investigates the effects of content familiarity and language ability (defined as general L2 proficiency) on the comprehension performance of low- and high-ability Saudi students of English as a foreign language. One hundred and thirty-two male
Yousif Alshumaimeri +1 more
core
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Word Familiarity Norms as a Test Case: Toward Methodological Standards for Word Norming Research
Normative databases of word properties are a fundamental resource in experimental psycholinguistics, enabling control of lexical variables and comparability across studies.
Silvia Benavides-Varela +5 more
core +1 more source
Why it is so hard to predict our partner's product preferences: The effect of target familiarity on prediction accuracy. [PDF]
Many buying decisions require predictions of another person's product attitudes. Yet, consumers are often inaccurate predictors, even for familiar others.
Lerouge, Davy, Warlop, Luk
core +2 more sources
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Unearthing Shan–shui in the contemporary park: landscape preferences are influenced by archetype
Archetypes, having both unique metaphysical and neurological underpinnings, are instrumental in forming the human experience of the external world. China, in particular, has demonstrated a rich historical tradition of cultivating and perpetuating Shan ...
Siyu Liu
doaj +1 more source

