Results 151 to 160 of about 10,136,889 (397)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

P32: CONSUMER ANAPHYLAXIS SIMULATION TRAINING FOR PARENTS AND FAMILIES OF CHILDREN WITH FOOD ALLERGIES [PDF]

, 2022
Early recognition of anaphylaxis and prompt administration of adrenaline are essential to reduce morbidity and mortality. Parental anxiety and lack of confidence are barriers to the use of adrenaline autoinjectors (AAIs). Consumer Anaphylaxis Simulation Training (CAST) is a course that aims to optimise parent and caregiver knowledge and confidence in effective management of allergic reactions and anaphylaxis.
openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

“I Could Stop and Breathe”: Early Implementation Results of a Short-Term Care Coordination Model for Children with Medical Complexity

International Journal of Integrated Care
Introduction: Children with medical complexity (CMC) are a vulnerable population with high healthcare utilisation and significant care coordination challenges.
Stephanie Hodgson, Ashleigh Griffiths, Christophe Lecathelinais, Camilla Askie   +3 more
doaj   +1 more source

A finiteness property on monodromies of holomorphic families [PDF]

, 2014
Thomas Delzant
openalex   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Qualitative exploration of gambling harm among UK veterans: normalisation, stigma and postservice escalation

BMJ Open
Objective This study explored the lived experiences of UK Armed Forces veterans affected by gambling-related harm. It examined how military culture, institutional practices and life transitions shaped gambling behaviours, barriers to help-seeking and the
Matt Fossey, Simon Dymond, Thomas Kersey, Chris Kay, Adanma Ekenna, Lauren R Godier-McBard, Dana Dekel, Hillary Engward   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Impact of Family Non-universal $Z^\prime$ Boson on Pure Annihilation $B_s \to π^+ π^-$ and $B_d \to K^+ K^-$ Decays [PDF]

, 2015
Ying Li, Wenlong Wang, D. Du, Zuohong Li, XU Hong-xia   +4 more
openalex   +1 more source