A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
The Effect of Family-Based Care on Stress, Anxiety, and Depression of Mothers With Premature Infants
Introduction: Giving birth to a premature neonate and its hospitalization are a stressful incident for parents and can lead to feelings of disability, stress, and subsequent anxiety and depression, especially in the mothers of infants.
Solmaz Pourkhani +3 more
doaj
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Effects of Family-Based Intervention for Childhood Obesity on Parental and Offspring Outcomes: A Systematic Review and Meta-Analysis. [PDF]
Zhang Y, Pang L, Yang S, Wu J.
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
The VIA Family 2.0 study: a randomized clinical trial evaluating a family-based intervention for children born to parents with mental illnesses-study protocol. [PDF]
Heuckendorff S +14 more
europepmc +1 more source
Evaluation of a group family-based intervention programme for adolescent obesity: the LITE randomised controlled pilot trial. [PDF]
Chew CSE +7 more
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Implementing a family-based intervention to promote healthy family routines in deprived neighborhoods - a feasibility study from Bremen, Germany. [PDF]
Schepan ML +9 more
europepmc +1 more source
Results of a Family-Based Intervention Promoting Healthy Weight Strategies in Overweight Hispanic Adolescents and Parents: An RCT. [PDF]
Prado G +7 more
europepmc +1 more source

