Results 41 to 50 of about 776,083 (234)

Review of Family-Based Psychosocial Interventions for Childhood Cancer [PDF]

Journal of Pediatric Psychology, 2010
To report the findings of a systematic review of family-based psychosocial interventions with pediatric oncology populations.A number of intervention studies documenting psychosocial interventions for childhood cancer populations, that incorporated multiple family members, were examined.Twenty-one studies were identified that met the criteria for ...
Emma, Meyler, Suzanne, Guerin, Gemma, Kiernan, Fin, Breatnach   +3 more
openaire   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Evaluating the Effectiveness of Community-Based Dementia Caregiver Intervention on Caregiving Burden, Depression, and Attitude Toward Dementia: A Quasi‐experimental Study

Clinical Interventions in Aging, 2022
Su Jung Lee,1 Hyun-Ju Seo,2 IL Han Choo,3 Seong Min Kim,4 Jeong Min Park,5 Eun-Young Yang,4 Yu Mi Choi6 1College of Nursing, Inje University, Gimhae, South Korea; 2College of Nursing, Chungnam National University, Daejeon, South Korea; 3Department of ...
Lee SJ, Seo HJ, Choo IH, Kim SM, Park JM, Yang EY, Choi YM   +6 more
doaj  

Authors’ Reply: Methodological Considerations for a Diabetes Family-Based eHealth Intervention

JMIR mHealth and uHealth, 2023

Yuheng Feng, Xiaohong Li
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Family-based intervention for controlling childhood obesity: An experience among Iranian children

International Journal of Preventive Medicine, 2013
Background: Treatment of childhood obesity is difficult, and successful management may differ in various areas with different cultural backgrounds. The present study was conducted to assess the effect of lifestyle modification family-based intervention ...
Fatemeh Esfarjani, Marjan Khalafi, Fatemeh Mohammadi, Asiyeh Mansour, Roshanak Roustaee, Negar Zamani Nour, Roya Kelishadi   +6 more
doaj  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

An Attachment-Based Family Therapy for Anxiety and Depression in Children: A Mixed-Methods Evaluation of BEST-Foundations

Children
Background/Objectives: Parent–child attachment and family relationships have been identified as risk factors for childhood internalising symptoms such as anxiety and depressive symptoms.
Kim Lee Kho, Andrew J. Lewis, Renita A. Almeida   +2 more
doaj   +1 more source