Results 111 to 120 of about 16,782,197 (406)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

FAMILY CERATOPOGONIDAE

open access: yesZootaxa, 2016
Two hundred and thirty five species of Ceratopogonids arranged in 28 genera are listed for Colombia, mostly Culicoides (112 species) and Forcipomyia (50 species). For each listed species, information on type locality, type category and sex, location of type material, species distribution, localities for Colombia and main references, is provided ...
Spinelli, Gustavo Ricardo, Wolff, Marta
openaire   +4 more sources

Integrative Family Therapy [PDF]

open access: yes, 1994
Reviewed Book: Olsen, David C. Integrative Family Therapy.
McCarl, Sandra A.
core   +1 more source

Histone deacetylases (HDACs): characterization of the classical HDAC family.

open access: yesBiochemical Journal, 2003
Transcriptional regulation in eukaryotes occurs within a chromatin setting, and is strongly influenced by the post-translational modification of histones, the building blocks of chromatin, such as methylation, phosphorylation and acetylation. Acetylation
Annemieke J M de Ruijter   +4 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Vivendo no método canguru a tríade mãe-filho-família Viviendo en el método canguru la tríade madre-hijo-familia Living the mother-child-family triad in the kangaroo method

open access: yesRevista Latino-Americana de Enfermagem, 2005
Este estudo tem como foco a vivência da família no método canguru (MC), com os objetivos de compreender o funcionamento da dinâmica familiar e apreender as transformações familiares pela permanência no método.
Laise Conceição Caetano   +2 more
doaj   +1 more source

Risky families: family social environments and the mental and physical health of offspring.

open access: yesPsychological bulletin, 2002
Risky families are characterized by conflict and aggression and by relationships that are cold, unsupportive, and neglectful. These family characteristics create vulnerabilities and/or interact with genetically based vulnerabilities in offspring that ...
R. Repetti, Shelley E. Taylor, T. Seeman
semanticscholar   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

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