Results 211 to 220 of about 13,930,990 (311)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

From Digital Anxiety to Empowerment in Older Adults: Cross-Sectional Survey Study on Psychosocial Drivers of Digital Literacy. [PDF]

JMIR Aging
Niu HJ, Li MH, Hsieh FY, Yu CC, Lin CT.
europepmc   +1 more source

Neighborhood Social Capital, Neighborhood Attachment, and Dental Care Use for Los Angeles Family and Neighborhood Survey Adults

, 2013
L. Donald, Richard M. Carpiano
openalex   +2 more sources

Evaluating the genus Cespitularia MilneEdwards & Haime, 1850 with descriptions of new genera of the family Xeniidae (Octocorallia, Alcyonacea) [PDF]

, 2018
Yehuda Benayahu, L.P. van Ofwegen, Catherine S. McFadden   +2 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Methodologies of Care: A Multimodal, Participatory Research Approach with Vulnerable Families Among South African Communities. [PDF]

Methods Protoc
Reid J, Johannes C, Wareley S, Ngadhi C, Nginase A, Demetriou K, Roman NV.   +6 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Experiences of Family Members Supporting Adults With Type 1 Diabetes: A Qualitative Study. [PDF]

Sci Diabetes Self Manag Care
Hellman P, Aho AC, Gillrell C, Wennick A, Axelsson M.   +4 more
europepmc   +1 more source

Family (Encyclopedia entry) [PDF]

, 2008
Coles, Roberta L.
core   +1 more source

A doubly robust test for gene-environment interaction in family-based studies of affected offspring [PDF]

, 2010
Beatrijs Moerkerke, Stijn Vansteelandt, Christoph Lange   +2 more
openalex   +1 more source