Results 131 to 140 of about 1,334,183 (304)

Family Matters: Adjustment to genetic cancer susceptibility testing [PDF]

open access: yes, 2006
Cancer is generally feared because it is associated with death and severe physical suffering. It is one of the most common causes of death in the Netherlands. Breast and colon cancer are the most prevalent types of cancer among women.
Oostrom, I.I.H. (Iris) van
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Successful Co-Parenting: A Family Stability Program [PDF]

open access: yes, 2014
IMPACT. 1: Increase participants' knowledge of how divorce impacts the child and techniques for fostering healthy adjustment. -- 2. Increase knowledge of positive communication skills and strategies for managing conflict between co-parents.
Irving, Carmen
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Defense Expenditure and Economic Growth under External Predation [PDF]

open access: yes
This paper develops a growth model of a country under a Hobbesian environment with international conflicts where national defense is the only way to prevent external predation.
Hu, An-Gang   +2 more
core   +1 more source

Family Adjustments and Parental Behaviour Among Mixed Marriage Families [PDF]

open access: yes, 2001
The primary purpose of the study was to determine the family adjustments and parental behaviour among mixed marriage families in Malaysia. The study also examined the association between selected factors of parental characteristics (age, sex, level of
Tan, Jo Pei
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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