Results 171 to 180 of about 3,068,795 (349)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

The role of family factors in explaining the women’s conflict of work and family roles

open access: yesفصلنامه خانواده پژوهی, 2016
This research aimed to investigate the relationship between family factors including socioeconomic status, family support, family attachment, family role overload, and family power structure with conflict of work and family roles among female employees ...
سیدعلیرضا افشانی   +1 more
doaj  

Examining a Comprehensive Model of Work and Family Demands, Work–Family Conflict, and Depressive Symptoms in a Sample of Correctional Supervisors

open access: green, 2019
Sara Namazi   +6 more
openalex   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Network analysis of workplace mobbing, work-family conflict, and mental health in adults from the general population. [PDF]

open access: yesFront Sociol
Espinoza Escobar JH   +3 more
europepmc   +1 more source

The Effect of Work Family Conflict on the Job Satisfaction Moderated by Chronic Regulatory Focus

open access: hybrid, 2019
Ade Irma Suryani   +5 more
openalex   +1 more source

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