Results 111 to 120 of about 289,586 (302)
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Chronic pain in a family doctor practice – meaning, assessment, and therapeutic options
Pain is a subjective, negative experience originating from stimuli that are currently or potentially damaging to the body’s tissues. Proper assessment of pain intensity is a clinically significant factor determining the further course of action for a ...
Jan Baran +7 more
core +1 more source
Confidentiality and treatment of young adults : proposals for amendments : the Gillick Proposition [PDF]
, 2015 The law does not determine between legal competency and actual competency of minors in medical issues. The objective of this paper is to put forward proposals to amend the legislation to redefine legal competency on the base that understanding should
Mangion, Ann Marie
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A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai +5 more
wiley +1 more source
NOTES FOR THE PRIMARY CARE TEACHERS: TEACHING DOCTOR-PATIENT COMMUNICATION IN FAMILY MEDICINE
, 2007 Doctor-patient communication skills are important in family medicine and can be taught and learned. This paper summarisesthe salient contents and main methods of the teaching and learning of doctor-patient communication, especially thoseapplicable to the
AR Yong Rafidah
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Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
, 2018 Introduction: Vaccination is the most effective method of infectious disease prevention. Contemporary technologies have created the possibility of producing vaccines against many diseases.
Bielska, Dorota Emilia +9 more
core +1 more source
Clinical Validation of Plasma p‐217tau in Neurological Diseases
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi +13 more
wiley +1 more source
Family doctor reminisces, 1992.
, 1992 Typescript reminiscences of Dr. Edgar R.
Hyde, Edgar R., died 2004;
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Social Capital and Having a Regular Family Doctor: Evidence from Longitudinal Data
, 2018 Evidence shows that access to a regular family doctor increases the likelihood of regular care; but about 15% of the Canadian population does not have access to a regular family doctor.
Devlin, Rose Anne +2 more
core +1 more source