Results 61 to 70 of about 289,586 (302)

Demands and satisfaction for family doctor contracted services in Tianjin City: A survey based on Kano model

Chinese General Practice Journal
Background: Family doctor contracted services have been widely implemented across China, yet challenges remain in improving coverage and service quality.
Wei Tingting, Zhang Zhibo, Li Ruolan, Liu Pei, Liu Ying, Pan Liping, Jia Jie, Zhang Na, Bian Bo   +8 more
doaj   +1 more source

THE PASSING OF THE FAMILY DOCTOR [PDF]

JAMA: The Journal of the American Medical Association, 1913
Lowell says, "Time makes ancient good uncouth." The whole trend of modern thought is to look for a new and better way. We travel, literally, in chariots with horses of fire. Jules Verne's dream of "Around the World in Eighty Days" has been more than realized and the stories of the Arabian Nights are equaled by the every-day events of common life. Even
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Policy Value and Practical Challenges of High-quality Development Contracted Family Doctor Services [PDF]

Zhongguo quanke yixue
As an important tool to promote hierarchical diagnosis and treatment, contracted family doctor services has experienced from pilot to full implementation, and is the core work of the current primary healthcare service system.
ZHANG Yan, AI Yunjie, WANG Chenzhou, GAO Hongxia
doaj   +1 more source

Doctor-patient communication and the consulting room use of computers in general practice. [PDF]

, 1988
This thesis examines the effects of general practitioners' use of a computer during consultations, on doctor-patlent communication and the delivery of care. The IBM Sheffield Primary Care System was used by GPs during routine consultations for the review
Brownbridge, Garry
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Factors Influencing the Demand for Long-term Family Doctor Contract in Community Health Service Centers [PDF]

Zhongguo quanke yixue
Background The number of patients with chronic diseases in the community of China is increasing annually. Family doctor contract service is an important way to promote people's health in China, and long-term family doctor contract will help to ...
XIONG Liufang, ZHOU Xiaozhao, MA Hanying, ZHAO Tiefu
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Connotation and Path for High-quality Development of Contracted Family Doctor Services in Aging Society [PDF]

Zhongguo quanke yixue
With the deepening of aging society in China, the needs of health service of the elderly are becoming more complex. This study discussed the connotation and path of high-quality development of contracted family doctor services in ageing society. The core
GAO Hongxia, MA Lei, LIU Suwei, ZHANG Yan
doaj   +1 more source