Results 101 to 110 of about 15,064,686 (342)

Secondhand Smoke Exposure and Brain Health Indicators in Cuban Preschoolers

Toxics
Secondhand smoke affects nearly 40% of children worldwide, leading to serious health and behavioral problems. Being neurotoxic, it poses potential risks for child health and learning.
Yaser Ramírez Benítez, Miriela Díaz Bringas, Rodneys Mauricio Jiménez-Morales, Ijang Bih Ngyah-Etchutambe, Linda S. Pagani   +4 more
doaj   +1 more source

Family farming an asset for the planet ... : Food security, biodiversity, climate, water, jobs, environment... family farms are tackling the challenges of the future! [PDF]

, 2014
Over its fifteen pages or so, the 2014 edition of the CIRAD brochure produced for the Paris International Agricultural Show illustrates to what extent and in what way family farming can address the challenges of providing jobs and alleviating poverty ...
Causse, Frédérique (ed.), Hébert, Anne (ed.), Rawski, Christine (ed.), Sourisseau, Jean-Michel (ed.)   +3 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Ecological Validity of Expressed Emotion in Early Psychosis

Frontiers in Psychiatry, 2019
Expressed emotion (EE) is an aspect of the family environment that influences the course of multiple forms of psychopathology. However, there is limited research about how EE dimensions [i.e., criticism and emotional over-involvement (EOI)] are expressed
Lídia Hinojosa-Marqués, Tecelli Domínguez-Martínez, Thomas R. Kwapil, Neus Barrantes-Vidal, Neus Barrantes-Vidal, Neus Barrantes-Vidal   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Influence of family environment on children's oral health: a systematic review.

Jornal de Pediatria, 2013
OBJECTIVE To review current models and scientific evidence on the influence of parents' oral health behaviors on their children's dental caries. SOURCES MEDLINE articles published between 1980 and June, 2012. Original research articles on parents' oral
A. Castilho, F. Mialhe, T. Barbosa, R. Puppin-Rontani   +3 more
semanticscholar   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Post Traumatic Growth for Gestational Diabetic Patients During COVID-19: Role of Partner Supportive Communication and Family Environment

International Journal of Women's Health, 2021
Zhidan Wang,1 Alishba Hania,2 Asma Muzaffar,2 Saadia Zia2 1School of Education Science, Jiangsu Normal University, Xuzhou, 221116, People’s Republic of China; 2Department of Psychology, Institute of Southern Punjab, Multan, PakistanCorrespondence ...
Wang Z, Hania A, Muzaffar A, Zia S
doaj