Results 101 to 110 of about 10,127,787 (252)

A network and mediation analysis on the associations between family environment and suicidal ideation in adolescents in a psychiatric clinical setting

open access: yesFrontiers in Psychiatry
BackgroundFamily environmental factors are known to contribute to adolescent suicidal ideation (SI), but how these factors interact and relate to SI needs further investigation.AimsTo examine how family factors interact with each other and are associated
Xing-Yan Liu   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Efectos de la pedagogía y el compromiso educativo sobre el logro académico de los estudiantes de educación media || Effects of pedagogy and educational commitment on the academic performance of middle school students

open access: yesRevista de Métodos Cuantitativos para la Economía y la Empresa, 2019
Este artículo estudia por medio de los modelos lineales jerárquicos, la hipótesis de incidencia positiva que las variables de pedagogía y compromiso educativo generan sobre el desempeño académico.
Astorquiza Bustos, Bilver Adrián
doaj  

Predicting Adverse Childhood Experiences from Family Environment Factors: A Machine Learning Approach

open access: yesBehavioral Sciences
Adverse childhood experiences (ACEs) are associated with profound long-term health and developmental consequences. However, current identification strategies are largely reactive, often missing opportunities for early intervention.
Nii Adjetey Tawiah   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Batchelor family collection

open access: yes, 1898
This collection consists of a diary, pages from the family scrapbook, and genealogical materials related to the Batchelor family of Little Rock ...
Batchelor family
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

The dynamic interplay between mental health difficulties and the family environment in early adolescence

open access: yesJCPP Advances
Background Adolescents experiencing mental health problems have an elevated risk of persisting difficulties as they transition into adulthood, stressing the importance of identifying modifiable factors impacting mental health during adolescence.
Ludvig Daae Bjørndal   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

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