Results 221 to 230 of about 1,611,335 (310)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Ignite the Parent-Child Bond: A Qualitative Exploration of Perspective and Need About Family Functioning Among Patients With Advanced Cancer and Their Adolescent Children. [PDF]

J Clin Nurs
Jiao J, Tan J, Yu J, Xiao J, Huang C, Xiao G, Xie J, Ding J, Tang S, Hunter A.   +9 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

The impact of type 2 diabetes on adolescent and family functioning and healthcare use: findings from the National Survey of Children's Health. [PDF]

Front Endocrinol (Lausanne)
Slesinger Roy NC, Bensignor MO, Grolnick WS, Scal PB.   +3 more
europepmc   +1 more source

Normal families of subharmonic functions [PDF]

Proceedings of the American Mathematical Society, 1956
openaire   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

The Impact of Social Media Disorder, Family Functioning, and Community Social Disorder on Adolescents' Psychological Distress: The Mediating Role of Intolerance to Uncertainty. [PDF]

Children (Basel)
Morillo-Sarto H, Torres-Vallejos J, Usán P, Barrada JR, Juarros-Basterretxea J.   +4 more
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Hospital-family collaborative DTT intervention to reduce the parenting stress through improving core symptoms and family functioning in children with autism spectrum disorder: a randomized controlled trial. [PDF]

Front Pediatr
Dai M, Li J, Chen X, Chen L, Tang X, Yu H, Qiu Y, Yang Y.   +7 more
europepmc   +1 more source