Results 121 to 130 of about 6,601,006 (311)

Integrating Mental Health in Welfare Evaluation: An Empirical Application [PDF]

open access: yes
This paper presents simple measures of individual and family mental health indices based on axiomatic foundations and integrates mental health into a neoclassical model that allows for proper substitution possibilities in the family preferences and ...
Das, Sanghamitra   +2 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Coordenação de unidades de saúde da família por enfermeiros: desafios e potencialidades

open access: yesRevista Gaúcha de Enfermagem
Trabalho que parte da reflexão de que, embora a Política Nacional de Atenção Básica não defina o enfermeiro como o coordenador das Unidades de Saúde da Família (USF), muitas vezes este profissional acaba assumindo tal função por diversos fatores que ...
Rafael Cerva Melo, Maria Élida Machado
doaj  

RESTRAINT TO SCHIZOPHRENIC FAMILY MEMBER AT HOME:FAMILY EXPERIENCE IN KENDAL DISTRICT CENTRAL JAVA [PDF]

open access: yes, 2015
Background: Schizophrenic is functional psychological disorder with main disruption on thinking process and disharmony. Schizophrenic patients often suffer deprivation by their family.
Anggraeni, Rina   +2 more
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Riscos psicossociais em equipes de saúde da família: carga, ritmo e esquema de trabalho [Psychosocial risks at family health teams: workload, pace, and work schedule]

open access: yesRevista Enfermagem UERJ, 2013
Este artigo teve o objetivo de analisar os riscos psicossociais relacionados à carga, ritmo e esquema de trabalho de equipes de saúde da família. O estudo é exploratório, descritivo utilizando-se a abordagem qualitativa dos dados.
Silvia Helena Henriques Camelo   +3 more
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Family needs on child development in the light of health promotion

open access: yesOnline Brazilian Journal of Nursing, 2008
This is an analytical exploratory research; its object is family health needs on child development apprehended by the dialectics between objective and subjective dimensions.
Verônica de Azevedo Mazza   +1 more
doaj  

The Update, August 24, 2009 [PDF]

open access: yes, 2009
The Update is a bi-weekly web newsletter published by the Iowa Department of Public Health's Bureau of Family Health. It is posted the second and fourth week of every month, and provides useful job resource information for departmental health care ...

core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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