Results 191 to 200 of about 19,986,902 (308)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Expanding family medicine in Latin America: health system drivers, workforce trends, and policy priorities for strengthening Primary Health Care. [PDF]

Front Med (Lausanne)
Mendoza-Rincón SE, Alvarado-Rodríguez MG, González-Ayala FL, Orellana-Navarrete LP, Trujillo-Sagel RI, De la Cruz-Torralva K, Caycedo-Guevara EL, Cuba-Fuentes MS, Rodríguez-Escobar MA.   +8 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Community-Based Hereditary Breast and Ovarian Cancer Family History Assessment and Genetic Testing among Spanish-Speaking Hispanic/Latina Women in California. [PDF]

Cancer Res Commun
Montoya DM, Corpuz AF, Gonzalez KE, Santos K, Reed A, Dang JHT, Chew HK, Polanco-Echeverry G, Tamayo LI, Hernandez MT, Martinez A, Ziv E, Neuhausen SL, Carvajal-Carmona LG, Duron Y, Fejerman L.   +15 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Family Physician Training Programs Worldwide: A Scoping Review of Criteria, Processes, and Challenges. [PDF]

Health Sci Rep
Ahmadi F, Amini-Rarani M, Jabbari A.
europepmc   +1 more source

Pregnancy and Family Health. A Programmed Text [PDF]

American Journal of Public Health, 1974
openaire   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

'I Call Them Our Village': Experiences Of Caregivers in Ontario's Extensive Needs Service. [PDF]

Child Care Health Dev
Rombos V, Salami ZO, Denomey N, Ferguson G, Baysarowich R, Newhook D, Sutherland S, Drmic I, Edwards J, Sharma S, Decker K, Milicevic T, Penner M.   +12 more
europepmc   +1 more source