Results 181 to 190 of about 20,077,418 (309)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

ReFraming The FaPMI (Families Where a Parent Has a Mental Illness) Program: Using a Participatory Action Research Approach to Create Change. [PDF]

Int J Ment Health Nurs
Allchin B, Morgan A, Clark C, Jewell H, Legge J, Schinas J, Mack H, McCall A, Cameron D, Chalmers A, Cosgriff C, Creswick A, Dickenson S, Forster I, Foster D, Fraser E, Harbor P, Hegarty M, Henley K, McCormack F, McGregor T, Nguyen AT, Rabbitt K, Sanders B, Sarikoudis V, Stead M, Stephenson N, Tesoriero L, Timmins G, Zinnack H.   +29 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

From Evidence to Action: Implementing Evidence-Based Interventions for Youth Substance Use Prevention Through Drug-Free Communities and CDC's ENGAGE Framework. [PDF]

J Public Health Manag Pract
Roehler DR, Thompson KR, Rayburn E, Smith G, Guarnizo J, Morales I.   +5 more
europepmc   +1 more source

Transvestites in the Family Health Program of Lapa

, 2008
Este texto apresenta o relato de experiência sobre o acolhimento das travestis no Programa Saúde da Família Lapa (PSF-Lapa), uma unidade de saúde de atenção básica, situada no bairro da Lapa, centro do Município do Rio de Janeiro. O PSF-Lapa é parte integrante do curso de Medicina da Universidade Estácio de Sá, em parceria com a Secretaria Municipal de
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

'So easy to destroy, so hard to build': understanding impacts of federal rule changes on the Title X program, 2018-2024. [PDF]

Health Aff Sch
Simmons RG, Baayd J, Quade C, Sanders JN, Widner A, Gero A, Compton S.   +6 more
europepmc   +1 more source

Evaluating the Impact of Community-Based Health Interventions: Evidence from Brazil's Family Health Program [PDF]

This paper analyzes the direct and indirect impacts of Brazil's Family Health Program. We estimate the effects of the program on mortality and on household behavior related to child labor and schooling, employment of adults, and fertility.
Soares, Rodrigo R., Rocha, Romero
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

School-Based Access to and Delivery of Oral Health Care. [PDF]

J Sch Health
Northridge ME, Gargano L, Mason MK.
europepmc   +1 more source