Results 241 to 250 of about 1,094,059 (311)

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Evaluation and adaptation of the Seamless Care Optimizing the Patient Experience Mental Health program. [PDF]

Can Fam Physician
Bolea B, Emam M, Smith J, Pomedli S, Picklyk C, Pariser P, Whitmore C.   +6 more
europepmc   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

"Never Just the Next Case File": A Qualitative Study Exploring Youth and Family Experiences Within Early Psychosis Coordinated Specialty Care. [PDF]

Early Interv Psychiatry
Zaheer R, Magel B, Vaz Q, Kozloff N, Ampofo A, Duda L, Durbin J, Foussias G, Sockalingam S, Zaheer J, Voineskos A, Soklaridis S.   +11 more
europepmc   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Heroes in motion - a six-year quality report and patient evaluation of a real-world exercise therapy program in pediatric oncology. [PDF]

Front Pediatr
Ohnmacht C, Kunder A, Benz S, Feuchtinger T, Puzik A.   +4 more
europepmc   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Local level health governance strengthening for universal health coverage: implementing the Bayang Malusog-Municipal Leadership Development Program in Aklan, Philippines. [PDF]

Health Policy Plan
Pepito VCF, Chung CA, Capeding TPJZ, Comia AA, Faraon ARG, Sedillo DS, Sualog MEC, Prieto-Carolino AC, Padilla PIP, Dayrit MM.   +9 more
europepmc   +1 more source