Results 141 to 150 of about 21,095,081 (312)

[The physiotherapist insertion in the family health program].

open access: yesCiencia & saude coletiva, 2011
Study of quali-quantitative character that had as its main objective, to map out the physiotherapist insertion in the Family Health Program (PSF) of the cities that compose a Regional Coordination of Health (CRS) in Rio Grande do Sul State. For this, after the identification of the cities that compose the referred coordination and professional ...
Kéllin Daneluz, Delai   +1 more
openaire   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

[Management nurses's attitudes in the family health program: view of the family health group].

open access: yesRevista brasileira de enfermagem, 2007
This article was a part of a research called Management Competences required from the nurse in the Family Health Program (FHP) and has as aim to identify the management attitudes required from the nurse to the manager of the nurse assistance in the Family Health Units (FHU) of a city of the "catarinense" seashore under a perception from these ...
Gladys Amélia Vélez, Benito   +1 more
openaire   +1 more source

Development of the Zimbabwe family planning program [PDF]

open access: yes
Family planning was introduced in Zimbabwe as a voluntary movement in the 1950s. Volunteers formed a Family Planning Association in the mid-1960s. The government became interested in family planning in the late 1960s after analysis of the 1961 population
Zinanga, Alex F.
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

FAMILY HEART HEALTH PROGRAM

open access: yesJournal of Cardiopulmonary Rehabilitation and Prevention, 2007
N. Elias   +5 more
openaire   +2 more sources

Social Science Research on Reproductive Health in the Philippines [PDF]

open access: yes
The accelerated increase in the world population has resulted in poverty, with women and children bearing the greatest burden. Hence, contraceptive research and family planning service delivery have been receiving the most attention.
Concepcion, Mercedes B.
core  

Home - About - Disclaimer - Privacy