Results 81 to 90 of about 1,055,978 (265)

[Bonding to implement the family health program at a basic health unit].

Revista da Escola de Enfermagem da U S P, 2009
Este estudio tuvo como objetivo conocer las estrategias de formación del vínculo entre usuarios y profesionales del Programa Salud de La Familia (PSF) de una unidad básica en Fortaleza-CE. Estudio descriptivo, de naturaleza cualitativa, realizado en los meses de agosto y septiembre de 2007 en Fortaleza-Ceará-Brasil.
Monteiro, Michele Mota, Figueiredo, Virgínia Paiva, Machado, Maria de Fátima Antero Sousa   +2 more
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Planning of Educational Actions by the Multidisciplinary Team of the Family Health Strategy

O Mundo da Saúde, 2013
The objective of the research was to identify how the health education actions are planned by the multidisciplinary team at the Family Health Strategy. A qualitative study was conducted in the Family Health Strategies belonging to a health regional with ...
Ana Carolina Vieira de Andrade, Magada Tessmann Schwalm, Luciane Bisognin Ceretta, Valdemira Santina Dagostin, Maria Teresa Soratto   +4 more
doaj  

Development of a theory-driven implementation strategy for cancer management guidelines in sub-Saharan Africa

Implementation Science Communications, 2020
Background Despite recent international efforts to develop resource-stratified clinical practice guidelines for cancer, there has been little research to evaluate the best strategies for dissemination and implementation in low- and middle-income ...
Rebecca J. DeBoer, Jerry Ndumbalo, Stephen Meena, Mamsau T. Ngoma, Nanzoke Mvungi, Sadiq Siu, Msiba Selekwa, Sarah K. Nyagabona, Rohan Luhar, Geoffrey Buckle, Tracy Kuo Lin, Lindsay Breithaupt, Stephanie Kennell-Heiling, Beatrice Mushi, Godfrey Sama Philipo, Elia J. Mmbaga, Julius Mwaiselage, Katherine Van Loon   +17 more
doaj   +1 more source

Breastfeeding and health promotion in the Family Health Program

, 2006
The objective of this study was to analyze the implementation of Health Promotion in the context of the Family Health Program. With that purpose, promotion of breastfeeding was used as a tracer condition. A field survey was performed, collecting data from 156 professionals and 286 mothers of babies until six months of age in five different ...
Becker, Daniel, Portela, Margareth Crisostomo   +1 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

O impacto sócio-cultural do Programa de Saúde da Família (PSF): uma proposta de avaliação

Cadernos de Saúde Pública
Este artigo desenvolve uma análise crítica das implicações de se definir a família como objeto da intervenção em saúde, tomando como referência o caso do Programa de Saúde da Família (PSF), propondo, simultaneamente, uma avaliação do impacto sócio ...
Leny Alves Bonfim Trad, Ana Cecília de Sousa Bastos   +1 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source