Results 121 to 130 of about 1,055,978 (265)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

[Approach to the elderly in family health programs].

Cadernos de saude publica, 2003
This article discusses the role of the Brazilian National Policy for Senior Citizens' Health in the promotion of healthy aging, preservation and improvement of functional capacity in the elderly, disease prevention, recovery of those who fall ill, and rehabilitation of those with limited functional capacity, will the goal of ensuring that senior ...
Jorge Alexandre, Silvestre, Milton Menezes, da Costa Neto   +1 more
openaire   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

40 hours in the Family Health Program?

, 2011
Recentemente um tema interessante alvoroçou os ânimos na lista de discussão virtual (sbmfc@googlegroups.com) da So­ciedade Brasileira de Medicina de Família e Comunidade (SB­MFC): a insatisfação com a carga horária de quarenta horas semanais na Estratégia de Saúde da Família (ESF).
openaire   +3 more sources

[Evaluation of the Family Health Program: a review].

Ciencia & saude coletiva, 2011
This is a bibliographic review on the evaluation studies of the Family Health Program (FHP). Lilacs and SciELO databases were consulted up to April, 2007. Full texts of 88 published articles were analyzed. It was observed that most articles were published between the years 2005 and 2006 in periodicals intended for the Health Service, being the main ...
Maicon Henrique, Lentsck, Ana Cláudia Garabeli Cavalli, Kluthcovsky, Fábio Aragão, Kluthcovsky   +2 more
openaire   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

[Management nurses's attitudes in the family health program: view of the family health group].

Revista brasileira de enfermagem, 2007
This article was a part of a research called Management Competences required from the nurse in the Family Health Program (FHP) and has as aim to identify the management attitudes required from the nurse to the manager of the nurse assistance in the Family Health Units (FHU) of a city of the "catarinense" seashore under a perception from these ...
Gladys Amélia Vélez, Benito, Luciana Corrêa, Becker   +1 more
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

FAMILY HEART HEALTH PROGRAM

Journal of Cardiopulmonary Rehabilitation and Prevention, 2007
N. Elias, R. Reid, L. Beaton, A. Pipe, S. Papadakis, P. O'Farrell   +5 more
openaire   +2 more sources