Results 131 to 140 of about 18,250,476 (284)

Desafios da operacionalização do Método da Roda: experiência em Sobral (CE)

Saúde em Debate
O texto discorre sobre os atuais desafios institucionais da operacionalização do Método da Roda, tendo como cenário o Sistema Municipal de Saúde de Sobral (CE).
Hermínia Maria Sousa da Ponte, Lucia Conde de Oliveira, Maria Marlene Marques Ávila   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Influence of sociodemographic factors and Family Health Strategy coverage on oral health promotion procedures: an analysis of Brazilian municipalities in 2019. [PDF]

J Clin Exp Dent, 2023
Paredes SO, de Lucena EH, Abreu MH, Forte FD.   +3 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Nursing performance and occupational risks in family health strategy: an integrative review. [PDF]

Rev Bras Med Trab, 2023
Pereira FWA, Braga DV, Xavier SPL, de Araújo MM, Dos Santos RL, Leite JCS.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Prevalência e fatores associados à capacidade funcional de idosos na Estratégia Saúde da Família em Montes Claros, Minas Gerais, Brasil

Revista Brasileira de Geriatria e Gerontologia
Objetivou-se mensurar o nível de capacidade funcional de idosos e suas associações, por meio de um estudo transversal com 516 residentes nas áreas circunscritas à Estratégia Saúde da Família no distrito de Grande Santos Reis, Montes Claros-MG.
Valnei Gomes Assis, Sara Nader Marta, Marta Helena Souza De Conti, Márcia Aparecida Nuevo Gatti, Sandra Fiorelli de Almeida Penteado Simeão, Alberto De Vitta   +5 more
doaj   +1 more source

Dispute for hegemony in the Family Health Strategy:

Revista Portal: Saúde e Sociedade
A visão ultraliberal dos governos de Michel Temer e Jair Bolsonaro, no contexto de recessão econômica do período 2016-2019, materializou políticas de austeridade e atos de governo que implicaram o processo de desmonte da Estratégia Saúde da Família da Atenção Básica do Sistema Único de Saúde.
openaire   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Performance of Family Health Strategy Nurses in LGBT+ Healthcare. [PDF]

Rev Bras Enferm, 2023
Paiva AT, Borges FA, Carloni PR, Silveira WJA, Ogata MN, Nóbrega MDPSS, Lourenção LG, García GC.   +7 more
europepmc   +1 more source