Results 161 to 170 of about 2,375,049 (287)

Collective Health Dental Practices in the Family Health Strategy

, 2016
The Family Health Strategy (FHS – Estratégia Saúde da Família/ESF) in Brazil aims to prioritize promotion and protection of the health of individuals and families within the community. It is based on the reorientation and reformulation of the work process in the context of the Single Health System (SHS).
Moura, Edson Lucio da Silva, Oliveira, Erick Ely Gomes de, Safh, Felipe, Nascimento, Liliane Silva do, Brandão, Gustavo Antônio Martins   +4 more
openaire   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Family and community guidance in adolescence: assessment in the family health strategy. [PDF]

Rev Lat Am Enfermagem, 2021
Queiroz RO, Moroskoski M, Shibukawa BMC, Uema RTB, Oliveira RR, Higarashi IH.   +5 more
europepmc   +1 more source

Health education in the Family Health Strategy: professionals’ perception

, 2015
Objetivo: Analizar la percepción de los profesionales de la salud de un equipo de Salud de la Familia sobre las actividades de educación en salud conducidas en la rutina del trabajo. Métodos: Investigación cualitativa realizada entre mayo y junio de 2012 a través de entrevista semiestructurada con ocho profesionales de salud de distintas categorías en ...
Silva, Juliana Rafaela Andrade da, Lemos, Emmanuelly Correia, Hardman, Carla Menêses, Santos, Simone José, Antunes, Maria Bernadete de Cerqueira   +4 more
openaire   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

User embracement in the Family Health Strategy in a city in the north of Minas Gerais, Brazil: a descriptive study, 2019-2020. [PDF]

Epidemiol Serv Saude, 2022
Barbosa SFA, Calixto PR, Silva RPFD, Almeida ER.   +3 more
europepmc   +1 more source

The impact of post-abortion care family planning counselling and services in low-income countries: a systematic review of the evidence [PDF]

, 2011
Unsafe abortions account for around 70,000 deaths each year, almost all of them in the developing world. Millions of women suffer permanent injury or chronic illness, adding a high cost to both individual families and health systems. Since the mid 1990s,
Bird, K, Kavanagh, J, Kwan, I, Tripney, J   +3 more
core  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

The long term effects of legalizing divorce on children [PDF]

We estimate the effect of divorce legalization on the long-term well-being of children. Our identification strategy relies on exploiting the different timing of divorce legalization across European countries. Using European Community Household Panel data,
Libertad González Luna, Tarja Viitanen
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