Results 51 to 60 of about 1,712,687 (313)

Developing a Just-in-Time Adaptive Mobile Platform for Family Medicine Education: Experiential Lessons Learned [PDF]

open access: yes, 2017
EASEL is a platform designed to provide just-in-time adaptive support to students during experiential learning interviews conducted as part of required work in an online course in a family medicine education program in a Midwestern urban university ...
Cooper, Shannon   +5 more
core  

Family healthcare and ADHD in france

open access: yesEuropean Psychiatry, 2011
IntroductionAttention Deficit Hyperactivity Disorder (ADHD) is a lifetime neuro-developmental disorder, which causes severe impairment in children and adolescents. A recent epidemiological study of children presenting with ADHD in France suggests an estimated prevalence of ADHD of 3.5-5.6%.ObjectivesA survey was conducted to gather information from the
M. Lecendreux, C. Gétin, K. Keddad
openaire   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Primary healthcare and family medicine in Kenya

open access: yesAfrican Journal of Primary Health Care & Family Medicine, 2014
No abstract available.
openaire   +5 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Impact of Family Presence in the Healthcare Setting [PDF]

open access: yes, 2014
Family presence at the patient’s bed side is promoted and encouraged within the healthcare arena. Healthcare staff strive for reports of satisfaction from patients and families.
McCabe, Michelle
core  

Food for talk: photo frames to support social connectedness for elderly people in a nursing home [PDF]

open access: yes, 2009
Social connectedness is crucial to someone’s well-being. A case study is conducted to test whether the social connectedness of elderly people living in a nursing home and their family and friends can be improved through a photo frame.
Biemans, Margit, Dijk, Betsy van
core   +4 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Doctor without borders : he's a physician who covers huge stretches of rural Texas -- and whose work provides key lessons about the fate and future of rural health care in America [PDF]

open access: yes, 2014
textDr. Jim Luecke, a rural family physician in Alpine, Texas, is one of six doctors responsible for thousands of patients across a sprawling 25,000 square foot remote region of the state.
Garcia-Ditta, Alexa Nicole 1986-
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

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