Results 71 to 80 of about 1,712,687 (313)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
DEFICIENCY OF VITAMIN D IS ASSOCIATED WITH FEMALE INFERTILITY
Фундаментальная и клиническая медицина, 2018 Aim. To determine the level of vitamin D in women with infertility in Kemerovo (Southwestern Siberia). Materials and Methods. We consecutively recruited 98 infertile women and 40 healthy women who applied for the routine examination in our medical center.
ASMIK G. Bochkarnikova +3 more
doaj
Barriers to cardiac rehabilitation delivery in a low-resource setting from the perspective of healthcare administrators, rehabilitation providers, and cardiac patients [PDF]
, 2019 Background: Despite clinical practice guideline recommendations that cardiovascular disease patients participate, cardiac rehabilitation (CR) programs are highly unavailable and underutilized. This is particularly true in low-resource settings, where the
Britto, Raquel +7 more
core +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Asthma management: an ecosocial framework for disparity research
, 2012 Background: Asthma management disparities (AMD) between African and White Americans are significant and alarming. Various determinants have been suggested by research frameworks that affect the unfair distribution of resources for asthma management to ...
Evans-Agnew, Robin A.
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Risk factors of chronic kidney diseases in Chinese adults with type 2 diabetes
Scientific Reports, 2018 In this study we conducted a cross sectional study to comprehensively evaluated the risk factors of chronic kidney disease (CKD) in a large sample of Chinese adults under primary care for type 2 diabetes mellitus (T2DM).
Lin Yang +6 more
doaj +1 more source
Granite Staters Skeptical Tax Law Will Benefit Them; Cite Health As Most Important Problem For Family 3/1/18 [PDF]
, 2018 New Hampshire residents are divided in their opinion of the recently passed tax law. Despite some predictions that most Americans will see at least a short-term reduction in the taxes they pay, only one-third believe their taxes will decrease or that ...
Survey Center, UNH
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source