Results 211 to 220 of about 12,436,746 (396)

Haplotype GWAS in Colorectal Cancer Patients with a Family History of Gastric or Prostate Cancer. [PDF]

Int J Mol Sci
Kudrén D, Waage L, Samola Winnberg J, Lindblad M, Li C, Lindblom A, Vermani L.   +6 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Association of Individual or Family History of Autoimmune Disease With Future Development of Type 1 Diabetes. [PDF]

Diabetes Metab Res Rev
Thomas N, Vaidya B, Leslie RD, Agardh D, Oram R, Dabelea D, Singh A, Chantzichristos D, Rewers M.   +8 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Higher systemic vascular resistance in individuals with a family history of hypertension. [PDF]

J Hypertens
Värri EKH, Tietäväinen J, Suojanen LJ, Choudhary MK, Mustonen J, Koskela JK, Pörsti IH.   +6 more
europepmc   +1 more source

Solvay: History of a Multinational Family Firm

, 2013
Kenneth Bertrams, Nicolas Coupain, Ernst Homburg   +2 more
openalex   +1 more source

Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer.

New England Journal of Medicine, 1999
L. Hartmann, D. Schaid, J. Woods, T. Crotty, J. Myers, P. G. Arnold, P. Petty, T. Sellers, Joanne L. Johnson, S. McDonnell, M. Frost, Robert B. Jenkins   +11 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Risk of colorectal cancer for carriers of mutations in MUTYH, with and without a family history of cancer.

Gastroenterology, 2014
Aung Ko Win, J. Dowty, S. Cleary, Hyeja Kim, D. Buchanan, Joanne P Young, M. Clendenning, C. Rosty, R. MacInnis, G. Giles, A. Boussioutas, F. Macrae, S. Parry, J. Goldblatt, J. Baron, Terrilea Burnett, L. Le Marchand, P. Newcomb, R. Haile, J. Hopper, M. Cotterchio, S. Gallinger, N. Lindor, K. Tucker, I. Winship, M. Jenkins   +25 more
semanticscholar   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source