Results 241 to 250 of about 12,436,746 (396)

Risk of asynchronous contralateral breast cancer in noncarriers of BRCA1 and BRCA2 mutations with a family history of breast cancer: a report from the Women's Environmental Cancer and Radiation Epidemiology Study.

Journal of Clinical Oncology, 2013
A. Reiner, E. John, Jennifer D. Brooks, C. Lynch, L. Bernstein, L. Mellemkjær, K. Malone, J. Knight, M. Capanu, S. Teraoka, P. Concannon, X. Liang, J. Figueiredo, Susan A. Smith, M. Stovall, M. Pike, R. Haile, Duncan C. Thomas, C. Begg, J. Bernstein   +19 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Family History: An Interview with Elder D. Todd Christofferson

, 2005
Ryan D. Christofferson
openalex   +1 more source

Effect of the Mediterranean Diet on the Lipid-Lipoprotein Profile: Is It Influenced by the Family History of Dyslipidemia?

, 2014
Alexandra Bédard, Louise Corneau, Marie‐Claude Vohl, Sylvie Dodin, Simone Lemieux   +4 more
openalex   +1 more source

Association between diabetes, family history of diabetes, and risk of nonalcoholic steatohepatitis and fibrosis

Hepatology, 2012
R. Loomba, M. Abraham, A. Unalp, L. Wilson, J. Lavine, E. Doo, N. Bass   +6 more
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Family History of Psychiatric Disorders as a Risk Factor for Post-Stroke Depression: A Systematic Review and Meta-Analysis. [PDF]

Neuropsychiatr Dis Treat
Zhang H, Wang Z, Li Z, Ma Q, Li G.
europepmc   +1 more source

Neural Correlates of Impulsivity in Healthy Males and Females with Family Histories of Alcoholism [PDF]

, 2013
Elise E. DeVito, Shashwath A. Meda, Rachel E. Jiantonio, Marc N. Potenza, John H. Krystal, Godfrey D. Pearlson   +5 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Signature ECG part 2: A normal ECG (?) and a malignant family history. [PDF]

Indian Pacing Electrophysiol J
Wilde A, Chockalingam P.
europepmc   +1 more source