Results 71 to 80 of about 4,817,785 (305)

Prevalence and predictors of prediabetes and its coexistence with high blood pressure in first-degree relatives of patients with type 2 diabetes: A 9-year cohort study

Journal of Research in Medical Sciences, 2020
Background: Prediabetes is strongly associated with high blood pressure; however, a little is known about prediabetes and high blood pressure comorbidity in the high-risk individuals.
Moluk Hadi Alijanvand, Ashraf Aminorroaya, Iraj Kazemi, Masoud Amini, Sima Aminorroaya Yamini, Marjan Mansourian   +5 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Family history of type 2 diabetes and the risk of type 2 diabetes among young and middle‐aged adults

Chronic Diseases and Translational Medicine
Background The prevalence of type 2 diabetes has been growing among younger and middle‐aged adults in the United States. A portion of this increase for this age group may be attributable to shared type 2 diabetes risks with family members.
Ken R. Smith, Huong Meeks, David Curtis, Barbara B. Brown, Kyle Kole, Lori Kowaleski‐Jones   +5 more
doaj   +1 more source

Some Molecular and Clinical Aspects of Genetic Predisposition to Malignant Melanoma and Tumours of Various Site of Origin

Hereditary Cancer in Clinical Practice, 2007
Based on epidemiological data we can assume that at least some malignant melanoma (MM) and breast cancer cases can be caused by the same genetic factors.
Dębniak Tadeusz
doaj   +1 more source

A Brief Version of the Family Background Questionnaire [PDF]

, 2009
Although it is lengthy. the Family Background Questionnaire provides reliable behaviorally specific family history information. Results from reliability and validity analyses suggest that a brief version of this instrument that assesses parental ...
Kalemeera, Augustine, Melchert, Timothy P.   +1 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Breast Cancer Family History and Behavioral Health Intentions: An Esteem-Relevant Mechanism Informed by the Terror Management Health Model

Current Oncology
The terror management health model (TMHM) offers a framework to investigate how concerns about mortality can motivate health-related behaviors through actions that bolster self-esteem.
Emily P. Courtney, Jamie L. Goldenberg
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Imaginer un avenir collectif, défendre des valeurs et s’adapter aux évolutions sociales et politiques : la politique familiale française

Sociologies, 2010
Drawing on his experience as editor-in-chief of Recherches Familiales, a peer-reviewed multidisciplinary journal on family issues, and director of research, studies and policy actions with UNAF, the official advocate and advisory body to the authorities ...
Gilles Séraphin
doaj