Results 121 to 130 of about 174,979,501 (287)
Witherspoon Family History - Accession 715 no. 114
, 2015 The Witherspoon Family History consists of a genealogy of the Witherspoon Family compiled by Joseph G. Wardlaw of York, South Carolina published by the Chester Genealogical Society in 1910.
Family History - Witherspoon Family
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Egyptian Journal of Medical Human GeneticsBackground Epilepsy is a major neurological disorder worldwide, with common risk factors identified including consanguinity, family history, and history of perinatal infections or insults.
Aisha AlShamsi, Sema Koruturk
doaj +1 more source
Blood SOD1 Activity in ALS Patients Receiving Tofersen Treatment
Annals of Neurology, EarlyView.Objective The antisense oligonucleotide tofersen is the first disease‐modifying drug for SOD1‐related amyotrophic lateral sclerosis (ALS) and was approved because of its ability to reduce SOD1 protein and neurofilament levels. The effect of tofersen on SOD1 activity is unclear but of clinical relevance because homozygous SOD1 mutations, linked to ...
Katharina Goehring +18 more
wiley +1 more source
Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome
Annals of Neurology, EarlyView.Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca +24 more
wiley +1 more source
Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients
Annals of Neurology, EarlyView.Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer +14 more
wiley +1 more source
Demographic and Clinical Characteristics of Epilepsy Patients in Ardabil City, Iran, 2022 [PDF]
Physical TreatmentsPurpose: Geographical location, demography, and ethnicity of a person can all affect epilepsy, a neurological condition. The prevalence and clinical features of epilepsy change with population dynamics and lifestyle, which affect healthcare management ...
Ghasem Fattahzadeh +3 more
doaj
Annals of Neurology, EarlyView.Objective Glycosylphosphatidylinositol (GPI)‐anchored proteins play critical roles in nervous system function. Pathogenic variants in genes involved in GPI‐anchor biosynthesis cause early‐onset multisystem disorders known as inherited GPI deficiencies. We describe a novel neuromuscular phenotype associated with PIGB deficiency.
Gorka Fernández‐Eulate +34 more
wiley +1 more source
Early prognosis of epilepsy. Effects of treatment in the first follow-up year
, 1986 A multicenter prospective investigation was conducted in 17 teaching and general hospital in Italy to assess the efficacy of the care delivered to previously untreated patients with epilepsy: 175 cases were included and allocated to monotherapy. Only 112
Collaborative Group for Epidemiology of Epilepsy +1 more
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Memory and Plasma pTau217 Refine Prognosis in Down Syndrome
Annals of Neurology, EarlyView.Individuals with Down syndrome (DS) are at high risk for Alzheimer's disease (AD), yet accessible tools for routine clinical screening of AD in individuals with DS remain limited. Using data from the Alzheimer Biomarker Consortium‐Down Syndrome (ABC‐DS), we show that integrating plasma pTau217 with performance on the modified cued recall task ...
Casey R. Vanderlip +62 more
wiley +1 more source
Ellerbe Family History - Accession 715 no. 27 [PDF]
, 2016 The Ellerbe Family History by Ronald William Ellerbe chronicles the origins and history of the Thomas Ellerby family of South Carolina from the 1670s to 1986.
Family History - Ellerbe Family +1 more
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