Results 221 to 230 of about 174,979,501 (287)

Theory of mind: A cognitive endophenotype of juvenile myoclonic epilepsy?

Epilepsia, EarlyView.
Abstract Objective Juvenile myoclonic epilepsy (JME), the most common idiopathic generalized epilepsy, is associated with neuropsychological and psychiatric comorbidities, including social cognition and theory of mind (ToM) deficits. The interplay between clinical features, social cognition, and their neural and genetic substrates remains poorly ...
Bernardo Crespo‐Pimentel, Lucas J. Rainer, Mario Braun, Martin Kronbichler, Patrick Langthaler, Lisa Kronbichler, Sarah Said‐Yürekli, Laura Zamarian, Hennric Jokeit, Kornelius Winds, Elias Legat, Eugen Trinka, Julia Höfler, Giorgi Kuchukhidze   +13 more
wiley   +1 more source

Risk of epilepsy in people with adult-onset hydrocephalus: insights from the UK Biobank. [PDF]

Neurol Sci
Buonocore J, Fortunato F, Fratto E, Sammarra I, Gambardella A, Quattrone A, Quattrone A.   +6 more
europepmc   +1 more source

Transcriptomic analysis reveals distinct expression patterns in focal cortical dysplasia

Epilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a common cause of drug‐resistant epilepsy in children and adults and exhibits substantial clinical and histopathological heterogeneity. However, morphological classification alone does not fully explain variability in epileptogenicity, disease severity, or treatment response.
Shivani Sonawane, Michal Hendrych, Michaela Ručková, Robin Jugas, Jan Vrbský, Martin Pail, Barbora Straka, Martina Strnadová, Lenka Krsková, Adam Vácha, Miroslav Koblížek, Barbora Splítková, Kateřina Koželková, Eliška Hloušková, Tereza Vaňková, Josef Zámečník, Štefánia Aulická, Markéta Hermanová, Pavel Kršek, Ondřej Slabý, Milan Brázdil   +20 more
wiley   +1 more source

Clinical Characteristics, Treatment Patterns, and Drug-Resistant Epilepsy Among Emirati Adults with Epilepsy. [PDF]

Neurol Ther
Alhammadi M, Alblooshi BK, Ahmed A, Alshaer M, Almazrouei R, Al-Shamsi S.   +5 more
europepmc   +1 more source

Severe skeletal fragility in SCN8A‐related developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Abstract In this child with a phenotype compatible with the SCN8A gain‐of‐function spectrum, more than 20 bone fractures were documented. Together with previously reported cases, these observations raise the possibility that skeletal fragility may represent an underrecognized feature of the clinical spectrum associated with pathogenic SCN8A variants ...
Adélia Maria de Miranda Henriques‐Souza, Kette D. Valente   +1 more
wiley   +1 more source

Low diagnostic yield of presurgical genetic testing in adult patients with epilepsy. [PDF]

Epilepsia
Jünemann C, Stuart A, Kaur N, Wiebe S, Jette N, Singh S, Borlot F, Knake S, Calgary Comprehensive Epilepsy Program Collaborators, Billie Au PY, Klein KM.   +10 more
europepmc   +1 more source

Impact of sedation on the reliability of magnetoencephalographic language mapping in pediatric epilepsy

Epilepsia, EarlyView.
Abstract Objective Magnetoencephalography (MEG) language mapping in pediatric epilepsy frequently requires sedation, which may alter cortical physiology and compromise the reliability of language lateralization. We hypothesized that sedation disrupts coupling between early auditory processing and higher order language networks, reducing the ...
Tao Song, Ryan R. Song, Carla Bodden, Rosario Deleon, Joe Cordova, Mingxiong Huang, Clifford Calley   +6 more
wiley   +1 more source

Prevalence and factors associated with intellectual impairment in children with epilepsy in two national referral hospitals in Uganda. [PDF]

Acta Epileptol
Arinda A, McVoy M, Abaatyo J, Kaddumukasa M, Sajatovic M, Katabira E.   +5 more
europepmc   +1 more source

Validation of the diagnosis of Lennox–Gastaut syndrome: Challenges and lessons learned

Epilepsia, EarlyView.
Abstract Objective Lennox–Gastaut Syndrome (LGS) is a severe developmental and epileptic encephalopathy characterized by multiple seizure types, cognitive impairment, and distinct electroencephalographic (EEG) findings. However, evolving diagnostic criteria, heterogeneous clinical features, and inconsistent electronic health record (EHR) documentation ...
Nicole Villalba, Marc Rosenman, Sandi Lam, Kelly G. Knupp, Liu Lin Thio, William P. Welch, Stephanie C. Randle, Rebecca Garcia‐Sosa, Laurel Reed, Tracy Dixon‐Salazar, Maura Carroll, Anup D. Patel   +11 more
wiley   +1 more source