Results 31 to 40 of about 1,207,506 (312)
Discrimination and Inequality in Housing in Ireland. ESRI Research Series, June 2018 [PDF]
, 2018 Access to housing is a fundamental human right protected under international conventions such as the Universal Declaration of Human Rights and the European Social Charter.
Fahey, Eamonn +3 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The Financialisation of Housing and Housing-related Family Support in Hungary
, 2023 Financial markets are making an ever larger impact on young adults’ access to housing worldwide. At the same time, housing-related family assistance also shapes young people’s housing conditions. Bence Kováts’s The Financialisation of Housing and Housing-related Family Support in Hungary examines how housing-related family assistance deeply embedded in
openaire +2 more sources
Service Connectors Model: Staffing and Cost Projections [PDF]
, 2001 The Mid-America Institute on Poverty (MAIP) has provided the information below as a guideline for understanding the likely staffing needs of a service connector model within Chicago Housing Authority (CHA) family developments.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Policy and Practice Brief: Supporting the Employment Outcomes of SSI and SSDI Beneficiaries in Section 8 or Subsidized Housing; A Model of Policy Supporting Effective Employment Practice [PDF]
, 2003 This brief provides an overview of the Family Self-Sufficiency Program administered by Housing and Urban Development. Comparisons and contrasts between Family Self- Sufficiency, and the Ticket to Work and Benefits Planning are drawn as is a template for ...
Golden, Thomas P.
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source