Results 101 to 110 of about 7,762,623 (311)
The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi +11 more
wiley +1 more source
CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen +11 more
wiley +1 more source
Background: The rising prevalence of marital conflict and its detrimental impact on individual and family well-being underscores the urgent need for effective interventions.
Seyedeh Farzaneh Jafari +2 more
doaj +1 more source
Contents: FPs and the Mental Health Act - Pierre MalliaThe mission of the Journal of the Malta College of Family Doctors (JMCFD) is to deliver accurate, relevant and inspiring research, continued medical education and debate in family medicine with the
Mallia, Pierre +1 more
core
ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral activity against multiple RNA ...
Rui Luo +9 more
wiley +1 more source
This study aimed to investigate the relationship between autonomy and intimacy of the family of origin and marital adjustment: with respect to the role of personality factors have been studied.
لیلا احمدی +2 more
doaj
The Power of Unity: Collective Action and Smallholder Agricultural Performance in West Africa
ABSTRACT We analyze the impact of collective action through farmer‐based organizations (FBOs) on smallholders' farm performance and income inequality in Ghana, Benin, The Gambia, and Mali. We find that FBO membership increases cereal yield in Ghana and The Gambia, legume yield in Mali, ruminant numbers in Benin and The Gambia, and total farm income in ...
Emmanuel Donkor +3 more
wiley +1 more source
Charting Intimacy in Refugee Families
The following is part of a series of short posts on photographic practice in Palestine. In the fall of 2014, Al-Azza’s work was exhibited at Tufts University, an event facilitated by Amahl Bishara and her students, a few of whom are featured here in the series.
openaire +2 more sources
Contents: Specialisation and training - Pierre MalliaJournal of the Malta College of Family Doctors The mission of the Journal of the Malta College of Family Doctors (JMCFD) is to deliver accurate, relevant and inspiring research, continued medical ...
Mallia, Pierre +1 more
core
Does Contract Farming Reduce Pesticide Use? Panel Data Evidence From Smallholder Farmers in China
ABSTRACT The inappropriate and excessive use of pesticides poses a major threat to human and ecosystem health in the agri‐food sector. While existing studies have examined the potential of contract farming to address this issue, most have focused on large‐scale farms and relied on small or transactional datasets, often leaving the role of crop‐specific
Zhihui Liang, Shan Jin, Matthew Gorton
wiley +1 more source

