Results 101 to 110 of about 264,078 (262)

'Doing What is Right': Researching Intimacy, Work and Family Life in Glasgow, 1945-1960 [PDF]

open access: yes
Understanding discursive shifts over the twentieth century in relation to family roles, paid work and care is essential to any critical review of contemporary family theory and policies. This paper charts aspects of these shifts.
Linda McKie, Sue Innes
core  

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

open access: yesAdvanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke   +14 more
wiley   +1 more source

Intimacy and Sexuality: Toward a Lifespan Perspective [PDF]

open access: yes, 2006
While the marketplace for sex-related goods and services, including drugs to remedy sexual dysfunction or enhance sexual experience, appears to be expanding exponentially, sexuality and intimacy are poorly understood aspects of human life and health.
Stacy Tessler Lindau
core  

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

open access: yesAdvanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng   +8 more
wiley   +1 more source

Neighborhood intimacy as perceived by women living in urban areas and its association with personal and social network characteristics

open access: yesInternational Journal of Preventive Medicine, 2012
Background: The purpose of this study is to determine association between personal, family, neighborhood, and social network characteristics and perceived intimacy in the neighborhood by the women.
Ali Alami   +4 more
doaj  

Is “Unconsummated Marriage” still an appropriate term? A snapshot of reality [PDF]

open access: yes, 2016
The most shared definition of Unconsummated Marriage (UM) refers to “the failure to perform successful sexual intercourse at the beginning of the marriage.
Fabrizi, A   +5 more
core  

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

open access: yesAdvanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang   +18 more
wiley   +1 more source

Effect of Prematurity, Birthweight, Maternal Stress, Socio-economic Status, and Mother-Child Intimacy on the Development of Preschool Children in Surakarta [PDF]

open access: yes, 2017
Background: Monitoring child development is an important step to prepare healthy children from the earliest age, both physically, spiritually, and socially. Monitoring child development can be done in the kindergarten.
Halu, S. A. (Silfia)   +2 more
core  

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

open access: yesAdvanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan   +11 more
wiley   +1 more source

Cien casos de intimidad expuestos a la mirada: un ensayo para casas alternativas [PDF]

open access: yes, 2017
Màster universitari en Estudis Avançats en Arquitectura: Projecte. Procés i ProgramacióLa intimidad es una cualidad que se da por sentado en el seno de la casa.
Zhang, Beilei
core   +1 more source

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