Results 141 to 150 of about 3,007,280 (347)
Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction
Advanced Science, EarlyView.Molecular foundation models can provide accurate predictions for a large set of downstream tasks. We develop MMELON, an approach that integrates pre‐trained graph, image, and text foundation models and validate our multi‐view model on over 120 tasks, including GPCR binding.
Parthasarathy Suryanarayanan +17 more
wiley +1 more source
Advanced Science, EarlyView.Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang +27 more
wiley +1 more source
Advanced Science, EarlyView.A transformative ferroelectric‐polarization strategy is employed to overcome the intrinsic limitations of tungsten bronze (TTB)‐type anode materials in metal‐ion batteries, using Bi3Nb17O47 as a model system. By exploiting the non‐centrosymmetric crystal structure and field‐induced ionic displacements, controlled structural engineering with ...
Xiaoming Lou +10 more
wiley +1 more source
Thermoelectric Property Mapping for High‐Performance Integrated MgAgSb‐MgCuSb System
Advanced Science, EarlyView.From the property mapping of the MgAgSb–MgCuSb system, both thermoelectric materials and corresponding interface materials are optimized: Ag‐rich compositions provide higher PF and zT, whereas Cu‐rich side yields superior transport properties and low contact resistance.
Jiankang Li +5 more
wiley +1 more source
Advanced Science, EarlyView.Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling +17 more
wiley +1 more source
Advanced Science, EarlyView.A MXene‐enhanced electrochemical sensor enables the rapid and direct detection of methamphetamine. Molecular simulations reveal that specific MXene surface functional groups act as key signal amplifiers by facilitating interfacial interactions. The sensor demonstrates high sensitivity and robust performance in complex biological matrices.
Ri Wang +7 more
wiley +1 more source