Results 241 to 250 of about 4,182,366 (344)

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Multidrug use in the Elderly Patients with Multimorbidity: A Great Problem in Family Medicine

, 2014
Süheyl Asma, Çiğdem Gereklioğlu, Aslı Korur, Ahmet Erdoğan   +3 more
openalex   +2 more sources

A cross-sectional study of United States family medicine residency programme director burnout: implications for mitigation efforts and future research

, 2020
Tamatha M. Psenka, John R. Freedy, Lisa Mims, Alec O. DeCastro, Carole Berini, Vanessa A. Díaz, Jennie B. Jarrett, Terrence E Steyer   +7 more
openalex   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Characteristics of family medicine physician associates/assistants in the United States. [PDF]

BMC Health Serv Res
Grubb B, Griffith CF, Bruza-Augatis M, Puckett K, Kozikowski A.   +4 more
europepmc   +1 more source

Patient safety principles in family medicine residency accreditation standards and curriculum objectives: Implications for primary care.

, 2016
Aliya Kassam, Nishan Sharma, Margot Harvie, Maeve O’Beirne, Maureen Topps   +4 more
openalex   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Community medicine, family medicine, and public health: The way forward

Indian Journal of Community and Family Medicine, 2015
Rajesh Kumar
doaj   +1 more source

Push Back and Push Family Medicine Forward, New AAFP President Urges. [PDF]

Ann Fam Med
Nosal S.
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source