Results 21 to 30 of about 1,924,278 (308)

23rd Family Medicine Scientific Conference 2021 [PDF]

open access: yesMalaysian Family Physician, 2021
Family Medicine Specialists Association Malaysia
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Apuntes sobre el desarrollo del modelo de reforma de la atención primaria y comunitaria de los años 80

open access: yesAtención Primaria Práctica, 2022
Resumen: El proceso de reforma de la atención primaria y comunitaria en España, iniciado en la década de los años 80, se planteó con unos objetivos teóricos ambiciosos que a lo largo de su desarrollo no se han visto cumplidos, al menos en un porcentaje ...
Amando Martín Zurro
doaj   +1 more source

The trouble with family medicine [PDF]

open access: yesFamily Practice, 1997
The trouble with family medicine is that the perceptual framework it uses to view the phenomena of health and illness is at variance with the frameworks traditionally used by medicine generally. This creates difficulties in communication between those in family medicine and those in other disciplines, and sometimes leads to misunderstanding of the ...
C S Chan, D V Chao, W E Fabb
openaire   +2 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Family medicine in Cuba

open access: yesMedwave, 2013
Over the past 50 years, the Cuban health system has been developing a roster of programs to ensure its social mission: to achieve a health status of the population consistent with the priority established by the highest authorities of the country.
Eduardo Alemañy Pérez   +1 more
doaj   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

open access: yesFEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling   +4 more
wiley   +1 more source

Family Medicine for Africa

open access: yesSouth African Family Practice, 2009
No abstract available.
Pierre J.T. de Villiers
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

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