Results 91 to 100 of about 3,847,256 (292)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Nursing ReportsBackground: After an older person moves into a nursing home, the next of kin often continues to participate in the care provided there. This participation in care may contribute valuable knowledge of the preferences and wishes of the older person ...
Helene Åvik Persson +4 more
doaj +1 more source
Lower Bounds for Pinning Lines by Balls [PDF]
, 2009 A line L is a transversal to a family F of convex objects in R^d if it intersects every member of F. In this paper we show that for every integer d>2 there exists a family of 2d-1 pairwise disjoint unit balls in R^d with the property that every subfamily
Cheong, Otfried +2 more
core +5 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
MedEdPORTAL, 2016 Introduction Improved team communication is essential in preventing errors in patient care. Based on TeamSTEPPS concepts, we developed this simulation case scenario to engage learners from various health care professions in interprofessional teamwork ...
Sharon Wilson, Linda Vorvick
doaj +1 more source
Coxeter groups and random groups [PDF]
, 2015 For every dimension d, there is an infinite family of convex co-compact reflection groups of isometries of hyperbolic d-space --- the superideal (simplicial and cubical) reflection groups --- with the property that a random group at any density less than
Calegari, Danny
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A knowledge, attitudes, and practices study on mutations among family members of women diagnosed with epithelial ovarian or fallopian tube cancer [PDF]
Obstetrics & Gynecology ScienceObjective BReast CAncer (BRCA) gene mutations increase the risk of epithelial ovarian and fallopian tube cancers. Genetic counseling and screening play a crucial role in identifying individuals at risk. Assessing knowledge, attitudes, and practices (KAP)
Sopita Prasertpakdi, Prapaporn Suprasert
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
A Different View of Stoma: Living with a Person with Stoma
Turkish Journal of Colorectal Disease, 2017 Stomas cause various physical, psychological and social problems among individuals and their family members both when they are created and in the post-hospital period.
Buket Çelik +3 more
doaj +1 more source