Results 71 to 80 of about 3,847,256 (292)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Voices for 2020: Ending Family Homelessness [PDF]

open access: yes, 2018
Ending family homelessness will require a wide variety of community-based strategies to ensure that every member of each family experiencing homelessness is offered the services and supports they need to thrive.
Bessell, Diane
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The applicability of the decisional conflict scale in nursing home placement decision among Chinese family caregivers: A mixed methods approach

open access: yes, 2017
This study aimed to 1) examine relationships between uncertainty, perceived information, personal values, social support, and filial obligation among Chinese family caregivers faced with nursing home placement of an older adult family member with ...
Chang, Yu-Ping   +2 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Disclosure of cancer diagnosis in China: the incidence, patients’ situation, and different preferences between patients and their family members and related influence factors

open access: yesCancer Management and Research, 2018
Yuxiu Liu,1,2 Jinhong Yang,3 Da Huo,3 Honghua Fan,3 Yufang Gao4 1Post-Doctoral Station of Clinical Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China; 2Department of Community Nursing, School of Nursing, Weifang Medical University ...
Liu Y, Yang J, Huo D, Fan H, Gao Y
doaj  

New members of the family [PDF]

open access: yesScience, 2016
Some publishers add new journal titles more often than I buy new shoes. The American Association for the Advancement of Science (AAAS), the publisher of Science , certainly cannot be accused of that, having grown to only four journal titles in 136 years.
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A mediation analysis of family members’ knowledge, attitudes, and practices in nutritional and dietary management for gastric cancer patients

open access: yesFrontiers in Medicine
BackgroundGastric cancer is a leading cause of global cancer mortality, especially in China, with high incidence and death rates. Nutritional status is crucial for prognosis, yet adherence to dietary guidelines remains low.
Cailian Liu, Min Wei, Lijuan Song
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

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