Results 71 to 80 of about 5,195,770 (298)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

A névelemek sorrendje és kulturális kongruenciája a Borsszem Jankó zsidó figuráinak névanyagában a 20. század első felében. [Order and cultural congruence of the elements in personal names for Jewish characters appearing in a Hungarian humour magazine entitled Borsszem Jankó in the first half of the 20th century]

open access: yesNévtani Értesítő, 2013
This study is based on previous research, which examined the name stock referring to Jewish characters occurring in a Hungarian humour magazine entitled Borsszem Jankó between 1901 and 1937.
Németh, Luca Anna
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Family medicine : present and future

open access: yes, 2013
Contents: Future prospects of the College - Pierre Mallia; The contemporary College and Council - Jason J Bonnici; Immersion pulmonary oedema in a scuba diver - Mario Saliba; eHealth and mHealth - bridging gaps in health care - Martina FalzonThe ...
Mallia, Pierre   +2 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Sistemas territoriais de financiamento rural: para pensar o caso brasileiro (Territorial Systems for Rural Financing: considering the Brazilian case) Doi: 10.5212/Emancipacao.v.13i2.0009

open access: yesEmancipação, 2014
No Brasil, a construção de sistemas territoriais de financiamento em zonas rurais passa pela inclusão de segmentos sociais pobres nas políticas de desenvolvimento rural.
Ademir Antonio Cazella   +1 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Hughes, first name unknown, Portland, Oregon, 1878

open access: yes, 1878
Hughes, first name unknown, Portland, Oregon ...
Towne, W.H., Portland, Oregon
core   +1 more source

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