Results 281 to 290 of about 5,684,732 (402)

Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen   +8 more
wiley   +1 more source

Meanings of nursing care for the family of patients in palliative care

open access: green, 2015
Marcos Vinícius da Silva Alves de LIMA   +1 more
openalex   +1 more source

Sudan at War With Itself: Civilian Devastation in the Civil War

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT A civil war is raging in Sudan between the Sudan Armed Forces (SAF) and the Rapid Support Forces (RSF) along with militia groups. Beginning on April 15, 2023, and continuing at least to this writing (October 15, 2025), civilian noncombatants have been subjected to bombings, beatings, torture, shootings, rape, and murder on a large scale. Since
Daniel Rothbart   +3 more
wiley   +1 more source

Secondary schools' preparation for roll‐out of Curriculum for Wales: Case studies of approaches to health and well‐being in the context of national education system reform

open access: yesThe Curriculum Journal, EarlyView.
Abstract Schools are increasingly positioned as key settings for promoting health behaviours and well‐being. Curriculum for Wales (CfW) represents major national reform of the Welsh education system, placing unprecedented focus on health and well‐being for learners in compulsory education (aged 3–16).
Rochelle Embling   +3 more
wiley   +1 more source

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