Results 141 to 150 of about 1,712,892 (388)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Postquantum Br\`{e}gman relative entropies and nonlinear resource theories
, 2019 We introduce the family of postquantum Br\`{e}gman relative entropies, based on nonlinear embeddings into reflexive Banach spaces (with examples given by reflexive noncommutative Orlicz spaces over semi-finite W*-algebras, nonassociative L$_p$ spaces ...
Kostecki, Ryszard Paweł
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Developing a Choice Theory-based Family Resilience Intervention Program
, 2023 Yasemin KAYGAS, Yaşar Özbay
openalex +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
On Finite Local Gauge Transformations in a Yang-Mills Field Theory with Invariant Gauge-Families [PDF]
, 1978 Keiichi Yokoyama +2 more
openalex +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Solving a family of $T\bar{T}$-like theories
, 2019 We deform two-dimensional quantum field theories by antisymmetric combinations of their conserved currents that generalize Smirnov and Zamolodchikov's $T\bar{T}$ deformation. We obtain that energy levels on a circle obey a transport equation analogous to
Floch, Bruno Le, Mezei, Márk
core