Results 51 to 60 of about 2,357,571 (386)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Prevalence of overweight and obesity in 15.8 million men aged 15–49 years in rural China from 2010 to 2014

Scientific Reports, 2017
Obesity has been increasing worldwide. Data on obesity status among men of reproductive age are scarce. This study aimed to assess the national prevalence and trend of overweight and obesity among reproductive-age men in rural China.
Yuan He, An Pan, Yuanyuan Wang, Ying Yang, Jihong Xu, Ya Zhang, Dujia Liu, Qiaomei Wang, Haiping Shen, Yiping Zhang, Donghai Yan, Zuoqi Peng, Frank B. Hu, Xu Ma   +13 more
doaj   +1 more source

Family Planning Market in India [PDF]

, 2017
This literature review captures existing knowledge across a range of products and players in India's family planning market. The product scope covers condoms, oral contraceptive pills, injectable contraceptives, intra-uterine devices, and male and female
Laura Amaya, Rishi Agarwal, Vignesh Shankar   +2 more
core  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Use of chlorhexidine digluconate 7.1% gel for umbilical cord care in selected regions in Northern Ghana: qualitative perspectives of key stakeholders

BMC Pregnancy and Childbirth
Background The Government of Ghana in 2017 included chlorhexidine (CHX) digluconate 7.1% gel in the essential medicines list to replace methylated spirit for umbilical cord care. However, there are limited studies around the use of the CHX gel.
Demi Priscilla Letsa Duah, Andrews Adjekwei Adjieteh, Selase Adjei, Kamil Fuseini, Akua Danquah Obeng-Dwamena, Joseph Addo-Yobo, Augustine Ankomah   +6 more
doaj   +1 more source

Nigeria Family Planning Bluepint (2014) [PDF]

, 2015
The Nigeria Family Planning Blueprint was created as a result of the commitments made by the Federal Government of Nigeria (FGON) at the 2012 London Summit on Family Planning to increase funding by an additional $8.35 million annually to bridge ...

core  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Criteria and practical guidance for determination of brain death in adults (BQCC version)

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
DOI: 10.3969/j.issn.1672-6731.2015.12 ...
Brain Injury Evaluation Quality Control National Health and Family Planning Commission
doaj  

Therapeutic effect of human umbilical cord-derived mesenchymal stem cells on injured rat endometrium during its chronic phase

Stem Cell Research & Therapy, 2018
Background Repair deficiency after endometrial injury is an important reason for intra-uterine adhesions, amenorrhea, and infertility in females. Bone marrow-derived mesenchymal stem cell (BMSC) transplantation is effective in repairing the damaged ...
Lu Zhang, Ying Li, Chun-Yi Guan, Shi Tian, Xiao-Dan Lv, Jian-Hui Li, Xu Ma, Hong-Fei Xia   +7 more
doaj   +1 more source

Improving access to highly effective emergency contraception: an assessment of barriers and facilitators to integrating the levonorgestrel IUD as emergency contraception using two applications of the Consolidated Framework for Implementation Research

Implementation Science Communications, 2022
Background Emergency contraception prevents unwanted pregnancy after sexual intercourse. New evidence has demonstrated that the levonorgestrel 52 mg IUD is a highly effective method of emergency contraception.
Rebecca G. Simmons, Jami Baayd, Sarah Elliott, Susanna R. Cohen, David K. Turok   +4 more
doaj   +1 more source