Results 51 to 60 of about 6,191,273 (313)

Therapeutic effect of human umbilical cord-derived mesenchymal stem cells on injured rat endometrium during its chronic phase

open access: yesStem Cell Research & Therapy, 2018
Background Repair deficiency after endometrial injury is an important reason for intra-uterine adhesions, amenorrhea, and infertility in females. Bone marrow-derived mesenchymal stem cell (BMSC) transplantation is effective in repairing the damaged ...
Lu Zhang   +7 more
doaj   +1 more source

FREQUENCY AND VARIANTS OF MENSTRUAL DISORDERS IN ADOLESCENTS WITH METABOLIC SYNDROME

open access: yesСхідноукраїнський медичний журнал, 2022
The problem of the correlation between reproductive disorders and metabolic syndrome (MS) is well known, but data on the frequency and nature of these disorders among adolescents are extremely limited.
Anna A. Sinkina   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Family Planning Decisions, Perceptions and Gender Dynamics among Couples in Mwanza, Tanzania: A Qualitative Study. [PDF]

open access: yes, 2013
Contraceptive use is low in developing countries which are still largely driven by male dominated culture and patriarchal values. This study explored family planning (FP) decisions, perceptions and gender dynamics among couples in Mwanza region of ...
Mosha, I.   +7 more
core   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The associations between maternal glycolipid metabolism and fetal growth in term births

open access: yesScientific Reports
This retrospective cohort study of 8,446 term pregnancies investigated the associations between maternal glycolipid metabolism and fetal growth. Neonates were classified as SGA, LGA, or AGA.
Jing Wang   +8 more
doaj   +1 more source

The branch performance tool: A methodological approach for continuous monitoring of programme efficiencies of service delivery interventions

open access: yesAfrican Evaluation Journal, 2019
Background: Programme efficiency is a vital factor in achieving Sustainable Development Goals (SDGs) in an environment of scarce resources. The branch performance tool (BPT) developed by the International Planned Parenthood Federation (IPPF) is an ...
Suchira S. Suranga   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Maternal exposure to ozone during pregnancy and risk of gestational diabetes in a Beijing pregnancy cohort study

open access: yesBMC Public Health
Background Gestational diabetes mellitus (GDM) exerts profound and lasting impacts on both maternal and offspring health, and the prevalence of GDM has been increasing.
Jing Wang   +8 more
doaj   +1 more source

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