Results 51 to 60 of about 521,418 (316)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

The branch performance tool: A methodological approach for continuous monitoring of programme efficiencies of service delivery interventions

African Evaluation Journal, 2019
Background: Programme efficiency is a vital factor in achieving Sustainable Development Goals (SDGs) in an environment of scarce resources. The branch performance tool (BPT) developed by the International Planned Parenthood Federation (IPPF) is an ...
Suchira S. Suranga, Kalhara Senadhira, R.M. Duminda K. Rajakaruna   +2 more
doaj   +1 more source

Improving access to highly effective emergency contraception: an assessment of barriers and facilitators to integrating the levonorgestrel IUD as emergency contraception using two applications of the Consolidated Framework for Implementation Research

Implementation Science Communications, 2022
Background Emergency contraception prevents unwanted pregnancy after sexual intercourse. New evidence has demonstrated that the levonorgestrel 52 mg IUD is a highly effective method of emergency contraception.
Rebecca G. Simmons, Jami Baayd, Sarah Elliott, Susanna R. Cohen, David K. Turok   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The associations between maternal glycolipid metabolism and fetal growth in term births

Scientific Reports
This retrospective cohort study of 8,446 term pregnancies investigated the associations between maternal glycolipid metabolism and fetal growth. Neonates were classified as SGA, LGA, or AGA.
Jing Wang, Di Wu, Bo Peng, Ya Zhang, Yuan Zhang, Xingyan Liu, Yuanyuan Wang, Li Lin, Xu Ma   +8 more
doaj   +1 more source

Repair of alveolar cleft bone defects by bone collagen particles combined with human umbilical cord mesenchymal stem cells in rabbit

BioMedical Engineering OnLine, 2020
Background Alveolar cleft is a type of cleft lip and palate that seriously affects the physical and mental health of patients. In this study, a model of the alveolar cleft phenotype was established in rabbits to evaluate the effect of bone collagen ...
Xue-Cheng Sun, Hu Wang, Jian-hui Li, Dan Zhang, Li-Qiang Yin, Yu-Fang Yan, Xu Ma, Hong-Fei Xia   +7 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Maternal exposure to ozone during pregnancy and risk of gestational diabetes in a Beijing pregnancy cohort study

BMC Public Health
Background Gestational diabetes mellitus (GDM) exerts profound and lasting impacts on both maternal and offspring health, and the prevalence of GDM has been increasing.
Jing Wang, Xingyan Liu, Di Wu, Bo Peng, Ya Zhang, Yuan Zhang, Yuanyuan Wang, Li Lin, Xu Ma   +8 more
doaj   +1 more source

Building an implementation framework to address unmet contraceptive care needs in a carceral setting: a systematic review

Health & Justice, 2023
Background The provision of contraceptive care for incarcerated individuals has been largely inconsistent and has contributed to, at best, inadequate care, and at worst reproductive abuses, violence, and coercion.
Douglas Routh, Rebecca Simmons, Jessica Sanders, Alexandra Gero, Hannah Aanderud Tanner, David K. Turok   +5 more
doaj   +1 more source