ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons +31 more
wiley +1 more source
A Qualitative Study on Men’s Involvement in Reproductive Health of Women among Auto-rickshaw Drivers in Bangalore Rural [PDF]
Background: Men’s reproductive health directly affects the partner’s reproductive health. Men also may serve as gatekeepers to women’s access to reproductive health services. “Male involvement” in reproductive health and family planning programmes is not
Gaikwad, VS, Murthy, TSM, Sudeepa, D
core +1 more source
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu +14 more
wiley +1 more source
'If I have only two children and they die. who will take care of me?' : a qualitative study exploring knowledge, attitudes and practices about family planning among Mozambican female and male adults [PDF]
Background: By focusing upon family planning counselling services, the Mozambican government has significantly enhanced the general health of female and male clients.
Capurchande, Rehana +3 more
core +2 more sources
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman +9 more
wiley +1 more source
Barriers to family planning use amongst the urban poor in Pakistan
This paper examines the determinants of family planning service use and the barriers in accessing family planning services among urban poor women in Pakistan.
Hennink, Monique, Stephenson, Rob
core
Assessing predictors of contraceptive use and demand for family planning services in underserved areas of Punjab province in Pakistan: results of a cross-sectional baseline survey [PDF]
Background: Although Pakistan was one of the first countries in Asia to launch national family planning programs, current modern contraceptive use stands at only 26% with a method mix skewed toward short-acting and permanent methods.
Abbas, Ghazunfer +8 more
core +4 more sources
Improving post-partum family planning services provided by female community health volunteers in Nepal: a mixed methods study. [PDF]
BACKGROUND: Family planning services in the post-partum period, termed post-partum family planning (PPFP) is critical to cover the unmet need for contraception, especially when institutional delivery rates have increased. However, the intention to choose
Arulkumaran, S +10 more
core +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source

